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Hepatocellular Adenomas Current Update on Genetics, Taxonomy, and Management

Hepatocellular Adenomas Current Update on Genetics, Taxonomy, and Management REVIEW ARTICLE Hepatocellular Adenomas: Current Update on Genetics, Taxonomy, and Management Alampady Shanbhogue, MD,* Shetal N. Shah, MD,Þ Atif Zaheer, MD,þ Srinivasa R. Prasad, MD,* Naoki Takahashi, MD,§ and Raghunandan Vikram, MBBS|| of incidental detection at least in part due to the widespread use Abstract: Hepatocellular adenomas (HCAs) are uncommon, benign of multiphase computed tomography (CT) or magnetic reso- hepatocellular neoplasms that commonly occur in young women. Recent nance imaging (MRI). Sex hormones, particularly estrogens, advances in pathology and cytogenetics have thrown fresh light on the seem to play a major role in the pathogenesis of HCAs. Hepa- pathogenesis of HCAs leading to classification of HCAs into 3 distinct tocellular adenomas occur predominantly in young adult women subtypes, each with a characteristic epidemiology, histopathology, on- (with a male-to- female ratio of 1:8Y10), with a mean age of cogenesis, and imaging findings. The aim of the article was to provide a 4,8 41 years, and are rarely seen in adult men and children. He- comprehensive review of contemporary taxonomy of HCAs, with an patocellular adenomas have been reported to grow remarkably emphasis on cross-sectional imaging findings and management. during pregnancy, sometimes with catastrophic consequences from rupture or hemorrhage. Medical literature http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Computer Assisted Tomography Wolters Kluwer Health

Hepatocellular Adenomas Current Update on Genetics, Taxonomy, and Management

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ISSN
0363-8715
eISSN
1532-3145
DOI
10.1097/RCT.0b013e31820bad61
pmid
21412084
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Abstract

REVIEW ARTICLE Hepatocellular Adenomas: Current Update on Genetics, Taxonomy, and Management Alampady Shanbhogue, MD,* Shetal N. Shah, MD,Þ Atif Zaheer, MD,þ Srinivasa R. Prasad, MD,* Naoki Takahashi, MD,§ and Raghunandan Vikram, MBBS|| of incidental detection at least in part due to the widespread use Abstract: Hepatocellular adenomas (HCAs) are uncommon, benign of multiphase computed tomography (CT) or magnetic reso- hepatocellular neoplasms that commonly occur in young women. Recent nance imaging (MRI). Sex hormones, particularly estrogens, advances in pathology and cytogenetics have thrown fresh light on the seem to play a major role in the pathogenesis of HCAs. Hepa- pathogenesis of HCAs leading to classification of HCAs into 3 distinct tocellular adenomas occur predominantly in young adult women subtypes, each with a characteristic epidemiology, histopathology, on- (with a male-to- female ratio of 1:8Y10), with a mean age of cogenesis, and imaging findings. The aim of the article was to provide a 4,8 41 years, and are rarely seen in adult men and children. He- comprehensive review of contemporary taxonomy of HCAs, with an patocellular adenomas have been reported to grow remarkably emphasis on cross-sectional imaging findings and management. during pregnancy, sometimes with catastrophic consequences from rupture or hemorrhage. Medical literature

Journal

Journal of Computer Assisted Tomography – Wolters Kluwer Health

Published: Mar 1, 2011

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