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M. Goyal, A. Demchuk, B. Menon, M. Eesa, J. Rempel, J. Thornton, D. Roy, T. Jovin, Robert Willinsky, B. Sapkota, D. Dowlatshahi, D. Frei, N. Kamal, W. Montanera, A. Poppe, Karla Ryckborst, F. Silver, A. Shuaib, D. Tampieri, David Williams, O. Bang, B. Baxter, P. Burns, H. Choe, J. Heo, C. Holmstedt, B. Jankowitz, M. Kelly, G. Linares, J. Mandzia, J. Shankar, S. Sohn, R. Swartz, P. Barber, S. Coutts, Eric Smith, W. Morrish, A. Weill, S. Subramaniam, A. Mitha, J. Wong, M. Lowerison, T. Sajobi, M. Hill (2015)
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J. Heit, M. Wintermark (2015)
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B. Campbell, P. Mitchell, T. Kleinig, H. Dewey, L. Churilov, N. Yassi, B. Yan, R. Dowling, M. Parsons, T. Oxley, Teddy Wu, M. Brooks, M. Simpson, F. Miteff, C. Levi, M. Krause, T. Harrington, K. Faulder, B. Steinfort, M. Priglinger, T. Ang, R. Scroop, P. Barber, B. McGuinness, T. Wijeratne, T. Phan, W. Chong, R. Chandra, C. Bladin, M. Badve, H. Rice, L. Villiers, Henry Ma, P. Desmond, G. Donnan, Stephen Davis (2015)
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Jeremy J. Heit, MD, PhD rain imaging is critical for the evaluation and treatment of acute In these 2 issues of Topics in Magnetic Resonance Imaging,we B ischemic stroke. Both computed tomography (CT) and mag- present a series of articles to review the recent advances in acute netic resonance imaging (MRI) are standardly used to make the ischemic stroke treatment, the advanced neuroimaging used for diagnosis of ischemic stroke, to exclude common ischemic stroke ischemic stroke evaluation, and how advanced neuroimaging is likely mimics, and to guide treatment decisions. Historically, the most to be used in the future for the treatment of patients beyond standard important role of brain CT and MRI is the exclusion of treatment time windows. These articles are written by national and intracranial hemorrhage, which is an absolute contraindication to international leaders in ischemic stroke imaging and treatment, and I treatment with intravenous thrombolysis. However, the role of brain wish to sincerely thank all of these authors for their thorough, imaging is rapidly changing in parallel with ischemic stroke thoughtful, and timely contributions. treatment advances. REFERENCES There has been a sea change in the treatment of ischemic stroke in the past 2 years with the unprecedented publication of 5 random- 1. Heit JJ, Wintermark M. Imaging selection for reperfusion therapy in acute ized trials that found an overwhelming benefit of endovascular ischemic stroke. Curr Treat Options Neurol. 2015;17:332. mechanical thrombectomy for the treatment of stroke due to occlu- 2. Berkhemer OA, Fransen PS, Beumer D, et al. A randomized trial of intraarterial 2–6 sion of a major cerebral artery. These endovascular trials have treatment for acute ischemic stroke. N Engl J Med. 2015;372:11–20. significant implications for radiologists, neuroradiologists, and other 3. Goyal M, Demchuk AM, Menon BK, et al. Randomized assessment of rapid neuroimagers, as the advanced neuroimaging techniques used in endovascular treatment of ischemic stroke. N Engl J Med. 2015;372:1019– most of these trials are being rapidly incorporated to neurointerven- tional practices around the world. Thus, the focus of brain imaging 4. Campbell BC, Mitchell PJ, Kleinig TJ, et al. Endovascular therapy for ischemic for acute ischemic stroke now must place a greater emphasis on stroke with perfusion-imaging selection. N Engl J Med. 2015;372:1009–1018. patient selection for endovascular therapy, and it is essential for the neuroimaging community to understand the clinical and imaging 5. Saver JL, Goyal M, Bonafe A, et al. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015;372:2285–2295. questions a neurointerventionalist must answer before proceeding with endovascular stroke treatment in order to design appropriate and 6. Jovin TG, Chamorro A, Cobo E, et al. Thrombectomy within 8 hours after rapid neuroimaging protocols. symptom onset in ischemic stroke. N Engl J Med. 2015;372:2296–2306. From the Stanford Hospital and Clinics, Department of Radiology, Stanford, CA. Address correspondence to Jeremy J. Heit, MD, PhD, Stanford Hospital and Clinics, 300 Pasteur Drive, Room S047, Stanford, CA 94305 (e-mail: jheit@stanford.edu). Copyright 2017 Wolters Kluwer Health, Inc. All rights reserved. DOI: 10.1097/RMR.0000000000000121 Topics in Magnetic Resonance Imaging Volume 26, Number 2, April 2017 www.topicsinmri.com 55 Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.
Topics in Magnetic Resonance Imaging – Wolters Kluwer Health
Published: Apr 1, 2017
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