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Global Risk Assessment and Coronary Artery Calcium Scoring in Low-Intermediate Risk Women

Global Risk Assessment and Coronary Artery Calcium Scoring in Low-Intermediate Risk Women Accurate atherosclerotic cardiovascular (ASCVD) risk assessment is needed for both women and men to identify and intervene in individuals at risk for ASCVD. Previously developed global risk scores, such as the Framingham Risk Score, have had many limitations, particularly in women who are routinely categorized as lower risk than men. 1 , 2 The newer ASCVD Risk Score 3 that makes up the current guidelines for assessment of cardiovascular risk has been shown to overestimate risk in women. 4 In addition, even in those with an optimal risk factor profile at the age of 55 years, there remains a substantial lifetime risk of ASCVD for both men and women (40% and 30%, respectively) who are unaccounted for by short-term (10 years) risk assessment. 5 See Article by Kelkar et al In this issue of Circulation: Cardiovascular Imaging , Kelkar et al 6 sought to determine the prognostic use of coronary artery calcium (CAC) scoring in a low-intermediate risk cohort of asymptomatic men and women. Despite the fact that CAC is currently not recommended as part of the risk stratification in low-intermediate risk individuals, this study demonstrated that the addition of CAC effectively identifies high-risk women, beyond what would http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Cardiovascular Imaging Wolters Kluwer Health

Global Risk Assessment and Coronary Artery Calcium Scoring in Low-Intermediate Risk Women

Gulati, Martha
Circulation: Cardiovascular Imaging , Volume 9 (4): e004817 – Apr 1, 2016
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References (16)

Copyright
© 2016 American Heart Association, Inc.
Subject
10069; 10071; 10073; 10128; 10132; Editorials
ISSN
1941-9651
eISSN
1942-0080
DOI
10.1161/CIRCIMAGING.116.004817
pmid
27072306
Publisher site
See Article on Publisher Site

Abstract

Accurate atherosclerotic cardiovascular (ASCVD) risk assessment is needed for both women and men to identify and intervene in individuals at risk for ASCVD. Previously developed global risk scores, such as the Framingham Risk Score, have had many limitations, particularly in women who are routinely categorized as lower risk than men. 1 , 2 The newer ASCVD Risk Score 3 that makes up the current guidelines for assessment of cardiovascular risk has been shown to overestimate risk in women. 4 In addition, even in those with an optimal risk factor profile at the age of 55 years, there remains a substantial lifetime risk of ASCVD for both men and women (40% and 30%, respectively) who are unaccounted for by short-term (10 years) risk assessment. 5 See Article by Kelkar et al In this issue of Circulation: Cardiovascular Imaging , Kelkar et al 6 sought to determine the prognostic use of coronary artery calcium (CAC) scoring in a low-intermediate risk cohort of asymptomatic men and women. Despite the fact that CAC is currently not recommended as part of the risk stratification in low-intermediate risk individuals, this study demonstrated that the addition of CAC effectively identifies high-risk women, beyond what would

Journal

Circulation: Cardiovascular Imaging – Wolters Kluwer Health

Published: Apr 1, 2016

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