Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice

Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced... Supplemental Digital Content is available in the text. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis Thrombosis and Vascular Biology Wolters Kluwer Health

Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice

Download PDF
12 pages

Loading next page...
 
/lp/wolters-kluwer-health/genetic-deficiency-of-traf5-promotes-adipose-tissue-inflammation-and-5eOhK5e4w4

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Wolters Kluwer Health
Copyright
© 2021 American Heart Association, Inc.
ISSN
1079-5642
eISSN
1524-4636
DOI
10.1161/atvbaha.121.316677
Publisher site
See Article on Publisher Site

Abstract

Supplemental Digital Content is available in the text.

Journal

Arteriosclerosis Thrombosis and Vascular Biology – Wolters Kluwer Health

Published: Oct 5, 2021

References

  • Obesity and cardiovascular disease.
    Ortega, FB; Lavie, CJ; Blair, SN
  • The cellular and molecular basis of translational immunometabolism.
    Norata, GD; Caligiuri, G; Chavakis, T; Matarese, G; Netea, MG; Nicoletti, A; O’Neill, LA; Marelli-Berg, FM
  • Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease.
    Fuster, JJ; Ouchi, N; Gokce, N; Walsh, K
  • TRAF molecules in cell signaling and in human diseases.
    Xie, P
  • Inflammatory pathways regulated by tumor necrosis receptor-associated factor 1 protect from metabolic consequences in diet-induced obesity.
    Anto Michel, N; Colberg, C; Buscher, K; Sommer, B; Pramod, AB; Ehinger, E; Dufner, B; Hoppe, N; Pfeiffer, K; Marchini, T
  • Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling.
    Wang, PX; Zhang, XJ; Luo, P; Jiang, X; Zhang, P; Guo, J; Zhao, GN; Zhu, X; Zhang, Y; Yang, S
  • Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
    Chatzigeorgiou, A; Seijkens, T; Zarzycka, B; Engel, D; Poggi, M; van den Berg, S; van den Berg, S; Soehnlein, O; Winkels, H; Beckers, L
  • TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor.
    Nakano, H; Oshima, H; Chung, W; Williams-Abbott, L; Ware, CF; Yagita, H; Okumura, K
  • TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling.
    Ishida, TK; Tojo, T; Aoki, T; Kobayashi, N; Ohishi, T; Watanabe, T; Yamamoto, T; Inoue, J
  • TRAF5 deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation.
    Missiou, A; Rudolf, P; Stachon, P; Wolf, D; Varo, N; Aichele, P; Colberg, C; Hoppe, N; Ernst, S; Münkel, C
  • TNF receptor-associated factor 5 limits the induction of Th2 immune responses.
    So, T; Salek-Ardakani, S; Nakano, H; Ware, CF; Croft, M
  • Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall.
    Missiou, A; Köstlin, N; Varo, N; Rudolf, P; Aichele, P; Ernst, S; Münkel, C; Walter, C; Stachon, P; Sommer, B
  • Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss.
    Dankel, SN; Fadnes, DJ; Stavrum, AK; Stansberg, C; Holdhus, R; Hoang, T; Veum, VL; Christensen, BJ; Våge, V; Sagen, JV
  • Overexpression of the obese (ob) gene in adipose tissue of human obese subjects.
    Lönnqvist, F; Arner, P; Nordfors, L; Schalling, M
  • Differential effects of fat and sucrose on body composition in A/J and C57BL/6 mice.
    Black, BL; Croom, J; Eisen, EJ; Petro, AE; Edwards, CL; Surwit, RS
  • Targeted disruption of ROCK1 causes insulin resistance in vivo.
    Lee, DH; Shi, J; Jeoung, NH; Kim, MS; Zabolotny, JM; Lee, SW; White, MF; Wei, L; Kim, YB
  • Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance.
    Su, WJ; Peng, W; Gong, H; Liu, YZ; Zhang, Y; Lian, YJ; Cao, ZY; Wu, R; Liu, LL; Wang, B
  • Obese diet-induced mouse models of nonalcoholic steatohepatitis-tracking disease by liver biopsy.
    Kristiansen, MN; Veidal, SS; Rigbolt, KT; Tølbøl, KS; Roth, JD; Jelsing, J; Vrang, N; Feigh, M
  • Tumor necrosis factor receptor-associated factor 5 (Traf5) acts as an essential negative regulator of hepatic steatosis.
    Gao, L; Wang, PX; Zhang, Y; Yu, CJ; Ji, Y; Wang, X; Zhang, P; Jiang, X; Jin, H; Huang, Z
  • The immune cells in adipose tissue.
    Ferrante, AW
  • Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance.
    Kraakman, MJ; Kammoun, HL; Allen, TL; Deswaerte, V; Henstridge, DC; Estevez, E; Matthews, VB; Neill, B; White, DA; Murphy, AJ
  • IL6 as a mediator of insulin resistance: fat or fiction?
    Allen, TL; Febbraio, MA
  • Regulation of PPARgamma function by TNF-alpha.
    Ye, J
  • CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity.
    Nishimura, S; Manabe, I; Nagasaki, M; Eto, K; Yamashita, H; Ohsugi, M; Otsu, M; Hara, K; Ueki, K; Sugiura, S
  • Obesity induces a phenotypic switch in adipose tissue macrophage polarization.
    Lumeng, CN; Bodzin, JL; Saltiel, AR
  • The adaptive immune system as a fundamental regulator of adipose tissue inflammation and insulin resistance.
    Winer, S; Winer, DA
  • The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6.
    Nagashima, H; Okuyama, Y; Asao, A; Kawabe, T; Yamaki, S; Nakano, H; Croft, M; Ishii, N; So, T
  • Epidemiology of obesity and diabetes and their cardiovascular complications.
    Bhupathiraju, SN; Hu, FB
  • Role of glucose effectiveness in the determination of glucose tolerance.
    Best, JD; Kahn, SE; Ader, M; Watanabe, RM; Ni, TC; Bergman, RN
  • The contribution of insulin-dependent and insulin-independent glucose uptake to intravenous glucose tolerance in healthy human subjects.
    Kahn, SE; Prigeon, RL; McCulloch, DK; Boyko, EJ; Bergman, RN; Schwartz, MW; Neifing, JL; Ward, WK; Beard, JC; Palmer, JP
  • Considerations and guidelines for mouse metabolic phenotyping in diabetes research.
    Alquier, T; Poitout, V
  • Metabolic syndrome, insulin resistance, and roles of inflammation–mechanisms and therapeutic targets.
    Romeo, GR; Lee, J; Shoelson, SE
  • Inflammatory cell recruitment in cardiovascular disease.
    Marchini, T; Mitre, LS; Wolf, D
  • Leukocyte heterogeneity in adipose tissue, including in obesity.
    Weinstock, A; Moura Silva, H; Moore, KJ; Schmidt, AM; Fisher, EA
  • The influence of obesity and different fat depots on adipose tissue gene expression and protein levels of cell adhesion molecules.
    Bošanská, L; Michalský, D; Lacinová, Z; Dostálová, I; Bártlová, M; Haluzíková, D; Matoulek, M; Kasalický, M; Haluzík, M
  • Leukocyte migration in adipose tissue of mice null for ICAM-1 and Mac-1 adhesion receptors.
    Robker, RL; Collins, RG; Beaudet, AL; Mersmann, HJ; Smith, CW
  • Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).
    Wolf, D; Bukosza, N; Engel, D; Poggi, M; Jehle, F; Anto Michel, N; Chen, YC; Colberg, C; Hoppe, N; Dufner, B
  • Adipocyte progenitor cells initiate monocyte chemoattractant protein-1-mediated macrophage accumulation in visceral adipose tissue.
    Kaplan, JL; Marshall, MA; C McSkimming, C; Harmon, DB; Garmey, JC; Oldham, SN; Hallowell, P; McNamara, CA
  • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity.
    Kanda, H; Tateya, S; Tamori, Y; Kotani, K; Hiasa, K; Kitazawa, R; Kitazawa, S; Miyachi, H; Maeda, S; Egashira, K
  • Macrophage inflammatory protein-1.
    Maurer, M; von Stebut, E
  • Chemokines control fat accumulation and leptin secretion by cultured human adipocytes.
    Gerhardt, CC; Romero, IA; Cancello, R; Camoin, L; Strosberg, AD
  • Macrophage inflammatory protein-1 alpha (MIP-1 alpha)/CCL3: as a biomarker.
    Bhavsar, I; Miller, CS; Al-Sabbagh, M; Preedy, V; Patel, V
  • Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction.
    Castellino, F; Huang, AY; Altan-Bonnet, G; Stoll, S; Scheinecker, C; Germain, RN
  • T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity.
    Wu, H; Ghosh, S; Perrard, XD; Feng, L; Garcia, GE; Perrard, JL; Sweeney, JF; Peterson, LE; Chan, L; Smith, CW
  • RANTES (regulated on activation, normal T cell expressed and secreted), inflammation, obesity, and the metabolic syndrome.
    Matter, CM; Handschin, C
  • Role of T cells in malnutrition and obesity.
    Gerriets, VA; MacIver, NJ
  • Normalization of obesity-associated insulin resistance through immunotherapy.
    Winer, S; Chan, Y; Paltser, G; Truong, D; Tsui, H; Bahrami, J; Dorfman, R; Wang, Y; Zielenski, J; Mastronardi, F
  • Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity.
    Lumeng, CN; Deyoung, SM; Bodzin, JL; Saltiel, AR
  • T cells in adipose tissue: critical players in immunometabolism.
    Wang, Q; Wu, H
  • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.
    Feuerer, M; Herrero, L; Cipolletta, D; Naaz, A; Wong, J; Nayer, A; Lee, J; Goldfine, AB; Benoist, C; Shoelson, S
  • Diminished levels of regulatory T cell subsets (CD8+Foxp3, CD4+Foxp3 and CD4+CD39+Foxp3) but increased Foxp3 expression in adipose tissue from overweight subjects.
    Núñez Ruiz, A; Cortés-Garcia, JD; Cortez-Espinosa, N; Herrera-Rojas, PI; Ruíz-Rodríguez, VM; Salgado-Bustamante, M; García-Hernández, MH; Reynaga-Hernández, E; Martínez-Jimenez, Vdel C; Portales-Pérez, DP
  • The human cell atlas.
    Regev, A; Teichmann, SA; Lander, ES; Amit, I; Benoist, C; Birney, E; Bodenmiller, B; Campbell, P; Carninci, P; Clatworthy, M
  • Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice.
    Wolf, D; Jehle, F; Michel, NA; Bukosza, EN; Rivera, J; Chen, YC; Hoppe, N; Dufner, B; Rodriguez, AO; Colberg, C
  • A decade of progress in adipose tissue macrophage biology.
    Hill, AA; Reid Bolus, W; Hasty, AH
  • ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism.
    Berg, AH; Combs, TP; Scherer, PE
  • Impact of obesity on IL-12 family gene expression in insulin responsive tissues.
    Nam, H; Ferguson, BS; Stephens, JM; Morrison, RF
  • Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation.
    Aizawa, S; Nakano, H; Ishida, T; Horie, R; Nagai, M; Ito, K; Yagita, H; Okumura, K; Inoue, J; Watanabe, T
  • Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death.
    Tada, K; Okazaki, T; Sakon, S; Kobarai, T; Kurosawa, K; Yamaoka, S; Hashimoto, H; Mak, TW; Yagita, H; Okumura, K
  • TNF-receptor-associated factors as targets for drug development.
    Zapata, JM
  • TRAF molecules in inflammation and inflammatory diseases.
    Lalani, AI; Zhu, S; Gokhale, S; Jin, J; Xie, P
  • Dietary fat, but not protein or carbohydrate, regulates energy intake and causes adiposity in mice.
    Hu, S; Wang, L; Yang, D; Li, L; Togo, J; Wu, Y; Liu, Q; Li, B; Li, M; Wang, G