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From prevention of mother-to-child transmission to child survival... and back Nigel Rollins and Wendy Mphatswe Centre for Maternal and Child Health Research, Purpose of review University of KwaZulu-Natal, Durban, South Africa At a time when highly effective drugs to prevent peripartum transmission of HIV are Correspondence to Nigel Rollins, Centre for Maternal readily available and affordable, HIV remains the single most important cause of the and Child Health, University of KwaZulu-Natal, Durban, death of infants and young children in southern and east Africa. South Africa Tel: +27 31 260 4352; fax: +27 31 260 4388; Recent findings e-mail: Rollins@ukzn.ac.za Evidence from the past 5 years highlights four main points. The survival of children born to HIV-infected mothers relies on the mothers remaining well and alive. Current Opinion in HIV and AIDS 2008, 3:180– Suboptimal feeding practices of HIV-exposed infants can significantly increase infant mortality aside of any impact on postnatal transmission of HIV. Antiretroviral drugs are now available that can reduce morbidity and mortality in infected women as well as the transmission of HIV to their infants. Finally, the inability of health systems to deliver prevention of mother-to-child transmission services is the greatest obstacle to reducing HIV infection among
Current Opinion in HIV and Aids – Wolters Kluwer Health
Published: Mar 1, 2008
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