Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Food for thought progress in understanding the causes and mechanisms of food allergy

Food for thought progress in understanding the causes and mechanisms of food allergy CE: Namrta; ACI/150302; Total nos of Pages: 6; ACI 150302 REVIEW URRENT Food for thought: progress in understanding the PINION causes and mechanisms of food allergy a,b a,f a,c,e,f a,c,e,f Sarah Ashley , Thanh Dang , Jennifer Koplin , David Martino , and d,e,f Susan Prescott Purpose of review The community burden of food allergy appears to be rising, yet the causes and mechanisms are not completely understood. The purpose of this review is to provide a snapshot of the state of play of IgE food allergies, with a focus on recent advances. Recent findings There are still wide discrepancies regarding measures and definitions of food allergy. Even recent studies still rely on food sensitization, self-reporting, or parent-reporting rather than more robust measures. Population-based sampling strategies using objective measures are underway in some countries. Emerging data suggest substantial geographical and ethnic differences in food sensitization and allergy. Trans- cutaneous sensitization, particularly in those with eczema or filaggrin mutations, has been posited as a potential mechanism, as well as gut microbiota and genetics/epigenetics. Treatments for food allergy are still lacking, yet progress is being made, and immunotherapy appears more effective than dietary avoidance. Non-IgE food allergy remains drastically under-explored. Summary http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Allergy and Clinical Immunology Wolters Kluwer Health

Food for thought progress in understanding the causes and mechanisms of food allergy

Current Opinion in Allergy and Clinical Immunology , Volume Publish Ahead of Print – Apr 1, 2015

Loading next page...
 
/lp/wolters-kluwer-health/food-for-thought-progress-in-understanding-the-causes-and-mechanisms-umgu7zbgYa

References (54)

Copyright
Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.
ISSN
1528-4050
eISSN
1473-6322
DOI
10.1097/ACI.0000000000000159
pmid
25899691
Publisher site
See Article on Publisher Site

Abstract

CE: Namrta; ACI/150302; Total nos of Pages: 6; ACI 150302 REVIEW URRENT Food for thought: progress in understanding the PINION causes and mechanisms of food allergy a,b a,f a,c,e,f a,c,e,f Sarah Ashley , Thanh Dang , Jennifer Koplin , David Martino , and d,e,f Susan Prescott Purpose of review The community burden of food allergy appears to be rising, yet the causes and mechanisms are not completely understood. The purpose of this review is to provide a snapshot of the state of play of IgE food allergies, with a focus on recent advances. Recent findings There are still wide discrepancies regarding measures and definitions of food allergy. Even recent studies still rely on food sensitization, self-reporting, or parent-reporting rather than more robust measures. Population-based sampling strategies using objective measures are underway in some countries. Emerging data suggest substantial geographical and ethnic differences in food sensitization and allergy. Trans- cutaneous sensitization, particularly in those with eczema or filaggrin mutations, has been posited as a potential mechanism, as well as gut microbiota and genetics/epigenetics. Treatments for food allergy are still lacking, yet progress is being made, and immunotherapy appears more effective than dietary avoidance. Non-IgE food allergy remains drastically under-explored. Summary

Journal

Current Opinion in Allergy and Clinical ImmunologyWolters Kluwer Health

Published: Apr 1, 2015

There are no references for this article.