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CASE REPORT Follicular and Mantle Cell Lymphoma Characteristics Present Simultaneously in the Same Lymph Node Petra Korac´, PhD,*w Tomislav Horvat, PhD,z Mirjana Mariana Kardum Paro, PhD,y Radmila Ajdukovic´,MD,8 Sonja Dzˇebro, MD,w and Mara Dominis, MD, PhDw + + + with rare centroblasts that are CD19 , CD20 ,CD22 , + + + + Abstract: Follicular lymphoma is composed of clonal germinal CD79a ,CD10 , BCL6 , BCL2 , and CD5 . center B cells. It shows a follicular pattern lacking mantle zones, t(14;18)(q32;q21), or in a few cases, some other BCL2 with a network of interfollicular dendritic cells. Transformation gene rearrangement is believed to be the primary genetic to more aggressive lymphomas is documented, but the only event in the development of FL. FL has 3 histologic connections to mantle cell lymphoma are described cases of grades based on the proportion of centroblasts. The first 2 composite lymphoma consisting of these 2 entities. We discuss grades are considered to be clinically less aggressive than + + here a case of a lymph node harboring CD20 , CD10 , the third, which in most cases is considered to be the + +/ + + + BCL2 , BCL6 ,
Applied Immunohistochemistry & Molecular Morphology – Wolters Kluwer Health
Published: Dec 1, 2013
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