Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Expression of OCT4 Transcription Factor in Cutaneous Neoplasia

Expression of OCT4 Transcription Factor in Cutaneous Neoplasia RESEARCH ARTICLE Expression of OCT4 Transcription Factor in Cutaneous Neoplasia Terrence M. Katona, DO,* Steven D. Billings, MD,* Rodolfo Montironi, MD,w Antonio Lopez-Beltran, MD,z and Liang Cheng, MD* primordial germ cells, and several neoplasms including 1–10 Abstract: The OCT4 transcription factor is a marker of seminoma, dysgerminoma, and embryonal carcinoma. pluripotency and is present in embryonic stem cells, primordial It is critical in the establishment and maintenance of 6,11–13 germ cells, and several neoplasms including seminoma, dysger- pluripotency. Recently, immunohistochemical ex- minoma, and embryonal carcinoma. Recently, immunohisto- pression of OCT 4 protein has been described in rare chemical expression of OCT4 protein has been described in the basal cells within human and canine epidermis. In cells within the basal layer of normal human and canine addition, OCT4 immunopositive cells have been identified epidermis. We have examined a series of basal cell carcinomas within the hair follicle bulge of human scalp. The latter and adnexal tumors of related histiogenesis, in an effort to finding was thought to indicate the presence of stem cells corroborate the above findings and to assess for expression of which may contribute to cutaneous plasticity. OCT4 protein in neoplasia of the infundibulo-apocrine-sebac- To the best of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Immunohistochemistry & Molecular Morphology Wolters Kluwer Health

Expression of OCT4 Transcription Factor in Cutaneous Neoplasia

Loading next page...
 
/lp/wolters-kluwer-health/expression-of-oct4-transcription-factor-in-cutaneous-neoplasia-sh1zF38Fgn

References (24)

ISSN
1541-2016
eISSN
1533-4058
DOI
10.1097/PAI.0b013e31803006eb
pmid
18091376
Publisher site
See Article on Publisher Site

Abstract

RESEARCH ARTICLE Expression of OCT4 Transcription Factor in Cutaneous Neoplasia Terrence M. Katona, DO,* Steven D. Billings, MD,* Rodolfo Montironi, MD,w Antonio Lopez-Beltran, MD,z and Liang Cheng, MD* primordial germ cells, and several neoplasms including 1–10 Abstract: The OCT4 transcription factor is a marker of seminoma, dysgerminoma, and embryonal carcinoma. pluripotency and is present in embryonic stem cells, primordial It is critical in the establishment and maintenance of 6,11–13 germ cells, and several neoplasms including seminoma, dysger- pluripotency. Recently, immunohistochemical ex- minoma, and embryonal carcinoma. Recently, immunohisto- pression of OCT 4 protein has been described in rare chemical expression of OCT4 protein has been described in the basal cells within human and canine epidermis. In cells within the basal layer of normal human and canine addition, OCT4 immunopositive cells have been identified epidermis. We have examined a series of basal cell carcinomas within the hair follicle bulge of human scalp. The latter and adnexal tumors of related histiogenesis, in an effort to finding was thought to indicate the presence of stem cells corroborate the above findings and to assess for expression of which may contribute to cutaneous plasticity. OCT4 protein in neoplasia of the infundibulo-apocrine-sebac- To the best of

Journal

Applied Immunohistochemistry & Molecular MorphologyWolters Kluwer Health

Published: Dec 1, 2007

There are no references for this article.