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RESEARCH REPORT Evaluating Hand Grip Strength Prior to Hematopoietic Stem Cell Transplantation as a Predictor of Patient Outcomes Charlotte Bailey, MA; Arash Asher, MD; Sungjin Kim, MS; Arvind Shinde, MD; Michael Lill, MD Samuel Oshin Comprehensive Cancer Institute, Cedars-Sinai, Los Angeles, California. Background and Purpose: The primary purpose of this study was to determine the predictive capacity of hand grip strength on overall survival among patients undergoing hematopoietic stem cell transplantation (HCT). Design: Retrospective chart review. Setting: Hand grip strength was measured at the time of HCT in an inpatient setting in 2009. Patients: Forty-nine patients with various hematologic malignancies. Intervention: Hand grip strength was performed using the dominant hand. The Functional Assessment of Chronic Illness Therapy–Fatigue (FACIT-F) was administered during the same visit. Chart abstraction was performed 5 years postassessment to obtain mortality data, Karnofsky Performance Status (KPS) at HCT, graft type, gender, comorbidity index, and age at HCT. Main Outcome Measure: Survival Results: Median follow-up time was 5.62 years. In multivariable analyses, higher hand grip strength was associated with shorter length of stay, higher FACIT-F total score, and higher FACIT-F subscale score in female patients only. Higher hand grip strength was associated with an improved overall survival
Rehabilitation Oncology – Wolters Kluwer Health
Published: Jul 1, 2018
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