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Enhanced Detection of Atypical Hyperplasia in Endometrial Polyps by PTEN Expression

Enhanced Detection of Atypical Hyperplasia in Endometrial Polyps by PTEN Expression Endometrial hyperplasia is difficult to recognize within endometrial polyps because of the background of randomly distributed irregular glands. The loss of expression of the PTEN oncogene is characteristic of endometrial cancers and clinically significant hyperplasia. Using immunohistochemical staining for the PTEN protein, we studied 12 endometrial polyps that were noted to contain foci of complex hyperplasia or http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Immunohistochemistry & Molecular Morphology Wolters Kluwer Health

Enhanced Detection of Atypical Hyperplasia in Endometrial Polyps by PTEN Expression

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ISSN
1541-2016

Abstract

Endometrial hyperplasia is difficult to recognize within endometrial polyps because of the background of randomly distributed irregular glands. The loss of expression of the PTEN oncogene is characteristic of endometrial cancers and clinically significant hyperplasia. Using immunohistochemical staining for the PTEN protein, we studied 12 endometrial polyps that were noted to contain foci of complex hyperplasia or

Journal

Applied Immunohistochemistry & Molecular MorphologyWolters Kluwer Health

Published: Mar 1, 2004

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