Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Effects of Two Forms of Hypertension on Atherosclerosis in the Hyperlipidemic Baboon

Effects of Two Forms of Hypertension on Atherosclerosis in the Hyperlipidemic Baboon We examined the relationship of hypertension and plasma renin activity to atherogenesis in 48 moderately hyperlipidemic (total serum cholesterol was about 200 mg/dl) baboons (Papiosp.). We used renal artery stenosis (two-kidney, one clip model) to produce hypertension associated with elevated plasma renin activity, and used cellophane wrapping of both kidneys (bilateral perinephritis model) to produce hypertension with normal renin activity. Renal artery stenosis and bilateral perinephritis increased both systolic and diastolic blood pressure by about 30 mm Hg. Renal artery stenosis approximately doubled, but bilateral perinephritis did not change plasma renin activity. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis Wolters Kluwer Health

Effects of Two Forms of Hypertension on Atherosclerosis in the Hyperlipidemic Baboon

Loading next page...
 
/lp/wolters-kluwer-health/effects-of-two-forms-of-hypertension-on-atherosclerosis-in-the-ubKyRTq8Ab

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Copyright
© 1985 by American Heart Association, Inc.
ISSN
0276-5047

Abstract

We examined the relationship of hypertension and plasma renin activity to atherogenesis in 48 moderately hyperlipidemic (total serum cholesterol was about 200 mg/dl) baboons (Papiosp.). We used renal artery stenosis (two-kidney, one clip model) to produce hypertension associated with elevated plasma renin activity, and used cellophane wrapping of both kidneys (bilateral perinephritis model) to produce hypertension with normal renin activity. Renal artery stenosis and bilateral perinephritis increased both systolic and diastolic blood pressure by about 30 mm Hg. Renal artery stenosis approximately doubled, but bilateral perinephritis did not change plasma renin activity.

Journal

ArteriosclerosisWolters Kluwer Health

Published: Sep 1, 1985

There are no references for this article.