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Effect of Intravenous Gadolinium-DTPA on Diffusion-Weighted Magnetic Resonance Images for Evaluation of Focal Hepatic Lesions

Effect of Intravenous Gadolinium-DTPA on Diffusion-Weighted Magnetic Resonance Images for... ORIGINAL ARTICLE Effect of Intravenous Gadolinium-DTPA on Diffusion-Weighted Magnetic Resonance Images for Evaluation of Focal Hepatic Lesions Fang-Ying Chiu, MS,* Jo-Chi Jao, MS,† Chiao-Yun Chen, MD,‡ Gin-Chung Liu, MD,‡ Twei-Shiun Jaw, MMS,‡ Yen-Yu Chiou, MB,‡ Feng-O Hsu, MB,‡ and Jui-Sheng Hsu, MD, PhD‡ Key Words: magnetic resonance imaging, apparent diffusion coef- Objective: Diffusion-weighted imaging (DWI) is usually performed ficient, diffusion-weighted imaging, hepatic lesions, gadolinium- before administration of intravenous contrast agents. Repetition of DTPA DWI is occasionally necessary after contrast administration, but the effects of contrast material on DWI and apparent diffusion coefficient (J Comput Assist Tomogr 2005;29:176–180) (ADC) values in the abdomen have not yet been fully examined. The purpose of this work is to assess whether administration of gadolinium- based contrast material significantly affects DWI and ADC values at iffusion is the thermally induced motion of water the focal hepatic lesions. Dmolecules in biologic tissues, also referred to as Bro- 1–3 Methods: The results of DWI at 3.0 T (Signa VH3; GE Medical wnian motion. The microscopic motion includes molecular Systems, Milwaukee, WI) were examined in 20 patients (age range: diffusion of water and microcirculation of blood in the 33–86 years, mean age = 68 years) who were http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Computer Assisted Tomography Wolters Kluwer Health

Effect of Intravenous Gadolinium-DTPA on Diffusion-Weighted Magnetic Resonance Images for Evaluation of Focal Hepatic Lesions

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Copyright
Copyright © 2005 by Lippincott Williams & Wilkins
ISSN
0363-8715
eISSN
1532-3145
DOI
10.1097/01.rct.0000157472.98277.5c
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Effect of Intravenous Gadolinium-DTPA on Diffusion-Weighted Magnetic Resonance Images for Evaluation of Focal Hepatic Lesions Fang-Ying Chiu, MS,* Jo-Chi Jao, MS,† Chiao-Yun Chen, MD,‡ Gin-Chung Liu, MD,‡ Twei-Shiun Jaw, MMS,‡ Yen-Yu Chiou, MB,‡ Feng-O Hsu, MB,‡ and Jui-Sheng Hsu, MD, PhD‡ Key Words: magnetic resonance imaging, apparent diffusion coef- Objective: Diffusion-weighted imaging (DWI) is usually performed ficient, diffusion-weighted imaging, hepatic lesions, gadolinium- before administration of intravenous contrast agents. Repetition of DTPA DWI is occasionally necessary after contrast administration, but the effects of contrast material on DWI and apparent diffusion coefficient (J Comput Assist Tomogr 2005;29:176–180) (ADC) values in the abdomen have not yet been fully examined. The purpose of this work is to assess whether administration of gadolinium- based contrast material significantly affects DWI and ADC values at iffusion is the thermally induced motion of water the focal hepatic lesions. Dmolecules in biologic tissues, also referred to as Bro- 1–3 Methods: The results of DWI at 3.0 T (Signa VH3; GE Medical wnian motion. The microscopic motion includes molecular Systems, Milwaukee, WI) were examined in 20 patients (age range: diffusion of water and microcirculation of blood in the 33–86 years, mean age = 68 years) who were

Journal

Journal of Computer Assisted Tomography – Wolters Kluwer Health

Published: Mar 1, 2005

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