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Downloaded from http://journals.lww.com/co-hivandaids by BhDMf5ePHKbH4TTImqenVJ2toCr/9wZZjwPUWvYES9l2nY+zyylnl33NGMK6MRsx on 10/23/2020 EDITORIAL URRENT The battle for survival between severe acute PINION respiratory syndrome coronavirus 2 and human beings a,b Zhiwei Chen In December 2019, the coronavirus disease 2019 SARS-CoV-2 is neither a direct progeny nor an engi- (COVID-19) outbreak was discovered among a neered variant of the SARS-CoV strain that caused group of pneumonia patients primarily associated the SARS epidemic in 2003. In fact, SARS-CoV-2 is with a seafood market in Wuhan city, China [1]. genetically distant from SARS-CoV, showing only Almost simultaneously, several groups of scientists 79.5% genomic homology [6,7]. Second, the closest confirmed that the causative agent was indeed a relative of SARS-CoV-2 was found to be a bat-derived novel coronavirus (CoV), now called severe acute CoV with 96% genomic homology. However, this respiratory syndrome coronavirus 2 (SARS-CoV-2) does not mean the bat CoV was a direct source of [1–4]. The prompt isolation and sequence sharing of SARS-CoV-2 [8], just like how humans did not origi- SARS-CoV-2 has remarkably led to rapid diagnosis nate directly from the rhesus monkey, despite that and paved the way for drug and vaccine discovery. the two species share about the similar 96% genomic By the
Current Opinion in HIV & AIDS – Wolters Kluwer Health
Published: Nov 1, 2020
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