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EDITORIAL URRENT Pathogenesis and immune response – editorial PINION a,b Dennis L. Stevens The role of science, common sense, and observa- benefits of vaccines or antimicrobial treatment and tions in improving the health of current humans our very own mothers diagnosed chicken pox, against pathogens. mumps, rubella, measles, whooping cough, strep There can be little controversy regarding the throat, scarlet fever, and typhoid fever in their very evolutionary importance of the interaction of own children. Because these were so common it was human immunologic responses to a vast array of virtually a rite of passage. Clearly, in my own expe- microbial virulence factors produced by invasive rience, it was rare that a physician would be microbes. Without question, humans have pre- involved in these childhood infections. If we were vailed despite huge pandemics and epidemics of sick, as defined by our mothers, we stayed at home microbes in all corners of the world over many in strict isolation. In the 1950s, many moms were centuries. stay at home moms and so caring for their child was Obviously, in more primitive times, thousands easier but also an act of love. of humans died of a variety of infectious diseases, During
Current Opinion in Infectious Diseases – Wolters Kluwer Health
Published: Jun 1, 2022
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