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Downloaded from http://journals.lww.com/co-hivandaids by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/02/2020 EDITORIAL URRENT Forging new frontiers in HIV and aging PINION a b Mary C. Masters and Kristine M. Erlandson As readers of this journal know well, antiretroviral future interventions. Hunt and Payne (pp. 101–109) therapy (ART) has transformed HIV from a terminal provide insight into measurement of mitochondrial disease to a now manageable, chronic condition. function, and examine the contribution of mito- Effective ART extends life expectancy of persons chondrial dysfunction to adverse aging in PWH, with HIV (PWH) near that of the general population. including the impact of prior ART. As the number of PWH with multimorbidity As a result, the number of older PWH continues to rise. The Centers for Disease Control estimates that grows, HIV clinical research must move beyond a nearly 50% of PWH in the United States are aged focus on isolated comorbidities. De Francesco, 50 years or more. This ‘graying’ of the HIV epidemic Sabin, and Reiss (pp. 110–117) discuss analytic appro- will continue: models from some European coun- aches to assessment of multimorbidity patterns in tries estimate that those aged 50 years or older will PWH. Improved understanding of these patterns account for more than
Current Opinion in HIV & AIDS – Wolters Kluwer Health
Published: Mar 1, 2020
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