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ORIGINAL ARTICLE Early Response of Hepatic Malignancies to Locoregional TherapyVValue of Diffusion-Weighted Magnetic Resonance Imaging and Proton Magnetic Resonance Spectroscopy Susanne Bonekamp, DVM, PhD,* Jialin Shen, MD,Þ Nouha Salibi, PhD,þ Hong C. Lai, PhD,* Jeff Geschwind, MD,* and Ihab R. Kamel, MD* However, most hepatocellular carcinoma (HCC) patients Purpose: The objective of our study was to determine the usefulness of (approximately 75%) are not candidates for curative treatments the diffusion-weighted magnetic resonance imaging and proton magnetic either because of poor liver function or the presence of advanced resonance spectroscopy ( H-MRS) of hepatic malignancies for the as- disease. Furthermore, tumor progression may prevent some sessment of response to locoregional treatment. 4 patients from undergoing transplantation. A wait of more than Methods: Forty-four patients (29 men; mean age, 58 years) with he- 6 months has been shown to be associated with a dropout rate of 5,6 patic malignancies were treated locally. Magnetic resonance imaging 23% to 40% from the waiting list. examinations obtained before and at 1 and 6 months after transarterial Locoregional therapy, including cryoablation, percutane- chemoembolization were analyzed retrospectively. Imaging criteria in- ous ethanol ablation, microwave ablation, radiofrequency ab- cluded change in tumor size, percentage of enhancement in
Journal of Computer Assisted Tomography – Wolters Kluwer Health
Published: Mar 1, 2011
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