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Dietary N‐3 Fatty Acids and Cardiovascular Diseases

Dietary N‐3 Fatty Acids and Cardiovascular Diseases Meeting Summary Dietary N-3 Fatty Acids and Cardiovascular Diseases Kaare R. Norum and Christian A. Drevon he International Union of Nutritional Sciences, Com- els of plasma antithrombin III as compared to the Danish T mittee IV/1 (Cardiovascular Disease and Hyperten- controls. Furthermore, the Eskimos had lower plasma sion), held a meeting of experts in Oslo, Norway, on March levels of low density lipoproteins (LDL), very low density 21-23,1985 to discuss the state of the art concerning n-3 lipoproteins (VLDL), and higher levels of high density lipo- fatty acids and cardiovascular diseases. The meeting is proteins (HDL) than the Danes. Most of these differences summarized below. could be induced experimentally in normal individuals by Dietary fatty acids have been associated with the occur- the addition of 10 g of cod liver oil extract in the diet. The rence of atherosclerosis and thrombosis in humans. Ex- mechanisms for these changes are mostly unknown. How- perimental studies have confirmed that dietary fats may ever, several of the effects are probably mediated through induce atherosclerosis. On the other hand, a diet with re- changes in prostanoid production, either by an inhibition of duced amounts of saturated fatty acids may cause regres- the usually http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis Wolters Kluwer Health

Dietary N‐3 Fatty Acids and Cardiovascular Diseases

Arteriosclerosis , Volume 6 (3) – May 1, 1986

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Copyright
© 1986 American Heart Association, Inc.
ISSN
0276-5047

Abstract

Meeting Summary Dietary N-3 Fatty Acids and Cardiovascular Diseases Kaare R. Norum and Christian A. Drevon he International Union of Nutritional Sciences, Com- els of plasma antithrombin III as compared to the Danish T mittee IV/1 (Cardiovascular Disease and Hyperten- controls. Furthermore, the Eskimos had lower plasma sion), held a meeting of experts in Oslo, Norway, on March levels of low density lipoproteins (LDL), very low density 21-23,1985 to discuss the state of the art concerning n-3 lipoproteins (VLDL), and higher levels of high density lipo- fatty acids and cardiovascular diseases. The meeting is proteins (HDL) than the Danes. Most of these differences summarized below. could be induced experimentally in normal individuals by Dietary fatty acids have been associated with the occur- the addition of 10 g of cod liver oil extract in the diet. The rence of atherosclerosis and thrombosis in humans. Ex- mechanisms for these changes are mostly unknown. How- perimental studies have confirmed that dietary fats may ever, several of the effects are probably mediated through induce atherosclerosis. On the other hand, a diet with re- changes in prostanoid production, either by an inhibition of duced amounts of saturated fatty acids may cause regres- the usually

Journal

ArteriosclerosisWolters Kluwer Health

Published: May 1, 1986

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