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Diet and Heart Disease Prudence, Probability, and Proof

Diet and Heart Disease Prudence, Probability, and Proof Editorials Diet and Heart Prudence, Probability, and Proof he argument about the "diet-heart disease question" has left the scientific T community exhausted and the public confused. It is time to take a look at the process whereby we have reached this impasse. In doing so, I do not intend to review in detail all the facts and fancies that have previously been brought to our attention. Instead, I wish to propose a resolution of the stalemate between the adherents and detractors of the diet-heart disease relationship. The evidence supporting the conclusion that diet and heart disease are causally linked is based roughly on the following types of observations: 1) Examination of various population groups has established an association between the consump- tion of cholesterol, saturated fat, and total fat with the prevalence of coronary heart disease in these countries. 2) These same dietary variables are also positively associated with serum cholesterol concentrations in these populations. 3) The feeding of various fat-modified diets to a variety of animals leads to variable de- grees of hyperlipidemia. 4) In humans, as well as in experimental animals, there is a strong correlation between the concentration of serum cholesterol, or that of certain lipoproteins, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis Wolters Kluwer Health

Diet and Heart Disease Prudence, Probability, and Proof

Arteriosclerosis , Volume 2 (2) – Mar 1, 1982

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Copyright
© 1982 by American Heart Association, Inc.
ISSN
0276-5047

Abstract

Editorials Diet and Heart Prudence, Probability, and Proof he argument about the "diet-heart disease question" has left the scientific T community exhausted and the public confused. It is time to take a look at the process whereby we have reached this impasse. In doing so, I do not intend to review in detail all the facts and fancies that have previously been brought to our attention. Instead, I wish to propose a resolution of the stalemate between the adherents and detractors of the diet-heart disease relationship. The evidence supporting the conclusion that diet and heart disease are causally linked is based roughly on the following types of observations: 1) Examination of various population groups has established an association between the consump- tion of cholesterol, saturated fat, and total fat with the prevalence of coronary heart disease in these countries. 2) These same dietary variables are also positively associated with serum cholesterol concentrations in these populations. 3) The feeding of various fat-modified diets to a variety of animals leads to variable de- grees of hyperlipidemia. 4) In humans, as well as in experimental animals, there is a strong correlation between the concentration of serum cholesterol, or that of certain lipoproteins,

Journal

ArteriosclerosisWolters Kluwer Health

Published: Mar 1, 1982

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