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Diagnosis of HIV-associated tuberculosis

Diagnosis of HIV-associated tuberculosis Downloaded from http://journals.lww.com/co-hivandaids by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/04/2020 REVIEW URRENT PINION Susan E. Dorman Purpose of review The current review highlights recent advances in tuberculosis (TB) diagnostics that are relevant for clinicians engaged in the care of HIV-positive adults. Recent findings The first section focuses on newly available tools, highlighting recent progress. The second section focuses on new diagnostic approaches that are not yet widely available or implemented, but have considerable potential to improve the management of TB/HIV coinfected persons. The final section speculates about future directions that may be fruitful. Summary Advances in Mycobacterium tuberculosis nucleic acid amplification-based genotypic tests stand to improve case detection and drug susceptibility testing in the near term. Identification of human gene expression signatures that are associated with TB and/or TB risk, and the identification of novel M. tuberculosis targets coupled with exploitation of advances in biosensor technology may transform TB diagnosis in the future. Keywords diagnosis, diagnostics, HIV, tuberculosis INTRODUCTION NEW TOOLS THAT HAVE ENTERED CLINICAL PRACTICE Tuberculosis (TB) in people living with HIV (PLHIV) has several facets that warrant special consideration Nucleic acid amplification tests during the development and clinical application of The cardinal features of nucleic acid amplification TB diagnostic tests. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in HIV & AIDS Wolters Kluwer Health

Diagnosis of HIV-associated tuberculosis

Dorman, Susan, E.
Current Opinion in HIV & AIDS , Volume 13 (6) – Nov 1, 2018
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References (31)

Publisher
Wolters Kluwer Health
ISSN
1746-630X
eISSN
1746-6318
DOI
10.1097/COH.0000000000000497
Publisher site
See Article on Publisher Site

Abstract

Downloaded from http://journals.lww.com/co-hivandaids by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/04/2020 REVIEW URRENT PINION Susan E. Dorman Purpose of review The current review highlights recent advances in tuberculosis (TB) diagnostics that are relevant for clinicians engaged in the care of HIV-positive adults. Recent findings The first section focuses on newly available tools, highlighting recent progress. The second section focuses on new diagnostic approaches that are not yet widely available or implemented, but have considerable potential to improve the management of TB/HIV coinfected persons. The final section speculates about future directions that may be fruitful. Summary Advances in Mycobacterium tuberculosis nucleic acid amplification-based genotypic tests stand to improve case detection and drug susceptibility testing in the near term. Identification of human gene expression signatures that are associated with TB and/or TB risk, and the identification of novel M. tuberculosis targets coupled with exploitation of advances in biosensor technology may transform TB diagnosis in the future. Keywords diagnosis, diagnostics, HIV, tuberculosis INTRODUCTION NEW TOOLS THAT HAVE ENTERED CLINICAL PRACTICE Tuberculosis (TB) in people living with HIV (PLHIV) has several facets that warrant special consideration Nucleic acid amplification tests during the development and clinical application of The cardinal features of nucleic acid amplification TB diagnostic tests.

Journal

Current Opinion in HIV & AIDS – Wolters Kluwer Health

Published: Nov 1, 2018

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