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Cytokine release syndrome: a primer for generalists

Cytokine release syndrome: a primer for generalists Summary Cytokine release syndrome (CRS) is an adverse drug reaction that is poorly understood but is likely to be increasingly common as more immunotherapeutics are being developed and licensed, principally in the treatment of cancer. Early recognition and aggressive treatment of this potentially rapidly fatal systemic inflammatory response syndrome (SIRS) is the key to a better outcome for this adverse drug reaction. aNational Institute for Health Research Guys and St Thomas’ Biomedical Research Centre bBritish Heart Foundation Centre, King's College London, UK Correspondence to Dr Henry Fok, Clinical Research Facility, 4th Floor, North Wing, St Thomas’ Hospital London, SE1 7EH, UK. Tel: +44 207188 4799; e-mail: henry.fok@kcl.ac.uk http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Adverse Drug Reaction Bulletin Wolters Kluwer Health

Cytokine release syndrome: a primer for generalists

Adverse Drug Reaction Bulletin , Volume 319 (1) – Dec 1, 2019

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References (22)

Publisher
Wolters Kluwer Health
ISSN
0044-6394
eISSN
2159-7774
DOI
10.1097/FAD.0000000000000044
Publisher site
See Article on Publisher Site

Abstract

Summary Cytokine release syndrome (CRS) is an adverse drug reaction that is poorly understood but is likely to be increasingly common as more immunotherapeutics are being developed and licensed, principally in the treatment of cancer. Early recognition and aggressive treatment of this potentially rapidly fatal systemic inflammatory response syndrome (SIRS) is the key to a better outcome for this adverse drug reaction. aNational Institute for Health Research Guys and St Thomas’ Biomedical Research Centre bBritish Heart Foundation Centre, King's College London, UK Correspondence to Dr Henry Fok, Clinical Research Facility, 4th Floor, North Wing, St Thomas’ Hospital London, SE1 7EH, UK. Tel: +44 207188 4799; e-mail: henry.fok@kcl.ac.uk

Journal

Adverse Drug Reaction BulletinWolters Kluwer Health

Published: Dec 1, 2019

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