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Current Outcomes of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Central Retinal Vein Occlusions: A Systematic Review and Meta-Analysis

Current Outcomes of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Central... Downloaded from http://journals.lww.com/apjoo by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/02/2020 REVIEW ARTICLE Current Outcomes of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Central Retinal Vein Occlusions: A Systematic Review and Meta-Analysis Kimberly Spooner, BAppSci, MMedHum,*† Thomas Hong, MScMed, PhD,* Samantha Fraser-Bell, PhD, FRANZCO,*† and Andrew Chang, PhD, FRANZCO*† CRVO into perfused (non-ischemic) and non-perfused (ischemic) Purpose: To evaluate the current anti–vascular endothelial growth subtypes centered on the extent of capillary non-perfusion as factor (anti-VEGF) treatments for macular edema due to central retinal 4 delineated by fluorescein angiography, which affects visual vein occlusions. 5 prognosis and has guided treatment. Non-perfusion leads to retinal Methods: PubMed, EMBASE, the Cochrane Library were neovascularization but more importantly neovascularization of systematically searched for studies between January 2013 and July 2018. the iris and angle potentially leading to neovascular glaucoma and Reference lists of published articles were searched and if necessary, 6,7 permanent severe visual loss. authors were contacted to provide additional data. Meta-analysis was In eyes with CRVO, cystoid macular edema (CME) occurs due performed using Comprehensive Meta-analysis software. The best- to leakage of fluid within the retina activated somewhat by release corrected visual acuity (BCVA), central foveal thickness (CFT), injection of vascular endothelial http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Asia-Pacific Journal of Ophthalmology Wolters Kluwer Health

Current Outcomes of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Central Retinal Vein Occlusions: A Systematic Review and Meta-Analysis

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References (55)

Publisher
Wolters Kluwer Health
ISSN
2162-0989
eISSN
2475-5028
DOI
10.22608/APO.2018543
Publisher site
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Abstract

Downloaded from http://journals.lww.com/apjoo by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/02/2020 REVIEW ARTICLE Current Outcomes of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Central Retinal Vein Occlusions: A Systematic Review and Meta-Analysis Kimberly Spooner, BAppSci, MMedHum,*† Thomas Hong, MScMed, PhD,* Samantha Fraser-Bell, PhD, FRANZCO,*† and Andrew Chang, PhD, FRANZCO*† CRVO into perfused (non-ischemic) and non-perfused (ischemic) Purpose: To evaluate the current anti–vascular endothelial growth subtypes centered on the extent of capillary non-perfusion as factor (anti-VEGF) treatments for macular edema due to central retinal 4 delineated by fluorescein angiography, which affects visual vein occlusions. 5 prognosis and has guided treatment. Non-perfusion leads to retinal Methods: PubMed, EMBASE, the Cochrane Library were neovascularization but more importantly neovascularization of systematically searched for studies between January 2013 and July 2018. the iris and angle potentially leading to neovascular glaucoma and Reference lists of published articles were searched and if necessary, 6,7 permanent severe visual loss. authors were contacted to provide additional data. Meta-analysis was In eyes with CRVO, cystoid macular edema (CME) occurs due performed using Comprehensive Meta-analysis software. The best- to leakage of fluid within the retina activated somewhat by release corrected visual acuity (BCVA), central foveal thickness (CFT), injection of vascular endothelial

Journal

The Asia-Pacific Journal of Ophthalmology – Wolters Kluwer Health

Published: May 1, 2019

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