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Takahiro Sato, K. Yamazaki, J. Toyota, Y. Karino, T. Ohmura, J. Akaike, Yasuaki Kuwata, T. Suga (2004)
Perforating veins in recurrent esophageal varices evaluated by endoscopic color Doppler ultrasonography with a galactose-based contrast agentJournal of Gastroenterology, 39
A. Shertsinger, G. Manuk'ian, V. Manuk'ian, V. Cherkasov, S. Zhigalova, V. Khovrin, Kara-Ali Aliev, D. Tsaava (2011)
[Pathogenesis of esophageal and gastric varicose veins formation in patients with liver cirrhosis].Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 6
Hojun Yu, S. Wilson (2012)
New Noninvasive Ultrasound Techniques: Can They Predict Liver Cirrhosis?Ultrasound Quarterly, 28
A. Berzigotti, R. Gilabert, J. Abraldes, C. Nicolau, C. Brú, J. Bosch, J. García‐Pagán (2008)
Noninvasive Prediction of Clinically Significant Portal Hypertension and Esophageal Varices in Patients With Compensated Liver CirrhosisThe American Journal of Gastroenterology, 103
Abdul Bhutto, A. Abbasi, Nazish Butt, A. Khan, S. Munir (2012)
Hepatic vein waveform in liver cirrhosis: correlation with child's class and size of varices.JPMA. The Journal of the Pakistan Medical Association, 62 8
F. Piscaglia, C. Nolsøe, C. Dietrich, D. Cosgrove, O. Gilja, M. Nielsen, T. Albrecht, L. Barozzi, M. Bertolotto, O. Catalano, M. Claudon, D. Clevert, J. Correas, M. D’Onofrio, F. Drudi, J. Eyding, M. Giovannini, M. Hocke, A. Ignee, E. Jung, A. Klauser, N. Lassau, E. Leen, G. Mathis, A. Saftoiu, G. Seidel, P. Sidhu, G. Haar, D. Timmerman, H. Weskott (2011)
The EFSUMB Guidelines and Recommendations on the Clinical Practice of Contrast Enhanced Ultrasound (CEUS): Update 2011 on non-hepatic applicationsUltraschall in der Medizin, 33
Thomas Joseph, M. Madhavan, K. Devadas, Vinayakumar Ramakrishnannair (2011)
Doppler Assessment of Hepatic Venous Waves for Predicting Large Varices in Cirrhotic PatientsSaudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association, 17
Subathra Adithan, B. Venkatesan, E. Sundarajan, V. Kate, R. Kalayarasan (2010)
Color Doppler evaluation of left gastric vein hemodynamics in cirrhosis with portal hypertension and its correlation with esophageal varices and variceal bleedThe Indian Journal of Radiology & Imaging, 20
A. Sanyal, J. Bosch, A. Blei, V. Arroyo (2008)
Portal hypertension and its complications.Gastroenterology, 134 6
Takahiro Sato, K. Yamazaki, J. Akaike (2009)
Diagnosis of Gastric Varices and Evaluation of the Effectiveness of Treatment Using Transabdominal Color Doppler UltrasonographyJournal of Ultrasound in Medicine, 28
Dong Liu, L. Qian, Jin-rui Wang, Xiang-Dong Hu, Lanyan Qiu (2014)
Hepatic perfusion parameters of contrast-enhanced ultrasonography correlate with the severity of chronic liver disease.Ultrasound in medicine & biology, 40 11
H. Stefanescu, M. Grigorescu, M. Lupsor, A. Maniu, D. Criṣan, B. Procopet, D. Feier, R. Badea (2011)
A new and simple algorithm for the noninvasive assessment of esophageal varices in cirrhotic patients using serum fibrosis markers and transient elastography.Journal of gastrointestinal and liver diseases : JGLD, 20 1
A. Burroughs (2011)
The Hepatic Artery, Portal Venous System and Portal Hypertension: The Hepatic Veins and Liver in Circulatory Failure
M. Tamano, M. Yoneda, K. Kojima, T. Hashimoto, T. Murohisa, Y. Majima, K. Kusano, Tetsuya Nakamura, H. Sugaya, A. Terano (2003)
Evaluation of esophageal varices using contrast-enhanced coded harmonic ultrasonography.Journal of gastroenterology and hepatology, 19 5
G. Garcia‐Tsao, A. Sanyal, N. Grace, W. Carey (2007)
Prevention and Management of Gastroesophageal Varices and Variceal Hemorrhage in CirrhosisThe American Journal of Gastroenterology, 102
M. Hashizume, S. Kitano, K. Sugimachi, K. Sueishi (1988)
Three‐dimensional view of the vascular structure of the lower esophagus in clinical portal hypertensionHepatology, 8
Takahiro Sato, K. Yamazaki, J. Toyota, Y. Karino, T. Ohmura, J. Akaike, Yasuaki Kuwata, T. Suga (2004)
Evaluation of arterial blood flow in esophageal varices via endoscopic color Doppler ultrasonography with a galactose-based contrast agentJournal of Gastroenterology, 40
Sanjay Sharma, R. Aggarwal (2007)
Prediction of large esophageal varices in patients with cirrhosis of the liver using clinical, laboratory and imaging parametersJournal of Gastroenterology and Hepatology, 22
(2008)
World Gastroenterology Organisation Practice Guideline: Esophageal Varices
Takahiro Sato, K. Yamazaki (2012)
Endoscopic Color Doppler Ultrasonography for Esophagogastric VaricesDiagnostic and Therapeutic Endoscopy, 2012
A. Colecchia, L. Montrone, E. Scaioli, M. Bacchi-Reggiani, A. Colli, G. Casazza, R. Schiumerini, L. Turco, A. Biase, G. Mazzella, L. Marzi, U. Arena, M. Pinzani, D. Festi (2012)
Measurement of spleen stiffness to evaluate portal hypertension and the presence of esophageal varices in patients with HCV-related cirrhosis.Gastroenterology, 143 3
Nagib Toubia, A. Sanyal (2008)
Portal hypertension and variceal hemorrhage.The Medical clinics of North America, 92 3
N. Carbonell, A. Pauwels, L. Serfaty, O. Fourdan, V. Lévy, R. Poupon (2004)
Improved survival after variceal bleeding in patients with cirrhosis over the past two decadesHepatology, 40
Takahiro Sato, K. Yamazaki, J. Toyota, Y. Karino, T. Ohmura, T. Suga (2003)
Evaluation of hemodynamics in esophageal varices. Value of endoscopic color Doppler ultrasonography with a galactose-based contrast agent.Hepatology research : the official journal of the Japan Society of Hepatology, 25 1
W. Jeong, Tae Kim, J. Sohn, Yongsoo Kim, Jinoo Kim (2015)
Severe Portal Hypertension in Cirrhosis: Evaluation of Perfusion Parameters with Contrast-Enhanced UltrasonographyPLoS ONE, 10
A. Wiechowska‐Kozłowska, K. Zasada, M. Milkiewicz, P. Milkiewicz (2011)
Correlation between Endosonographic and Doppler Ultrasound Features of Portal Hypertension in Patients with CirrhosisGastroenterology Research and Practice, 2012
M. Kim, K. Suk, S. Baik, Hyoungnyoun Kim, Young Kim, S. Cha, Hwa-Ryun Kwak, Mee‐Yon Cho, H. Park, Hyo Jeon, So Park, B. Kim, J. Hong, K. Jo, Jae Kim, H. Kim, S. Kwon, S. Chang, G. Baik, D. Kim (2012)
Hepatic vein arrival time as assessed by contrast‐enhanced ultrasonography is useful for the assessment of portal hypertension in compensated cirrhosisHepatology, 56
The purpose of this study was to clarify the usefulness of contrast-enhanced ultrasonography (CEUS) for the diagnosis of esophageal varices (EVs) in patients with cirrhosis. A total of 81 cases (56 patients with EVs and 25 control subjects without EV) were examined by CEUS and by esophagogastroduodenoscopy. According to the esophagogastroduodenoscopy results, we divided the subjects into 3 groups: G0, G1, and G2. The G0 group had 25 patients who exhibited no liver abnormality other than liver cyst or hemangioma without EVs, G1 comprised 9 patients with small EVs and 13 with medium EVs. G2 was composed of 34 cases of severe EVs. Under CEUS, the following parameters were measured: the thickness of double-layer mucosa and submucosa in the lower esophagus (Tm), the maximum anteroposterior diameter of the lower esophagus (De), and the ratio of Tm to De (Tm/De). Time-intensity curves of the lower esophagus and aorta were drawn using QLAB software. One-factor analysis of variance was used to compare means between the 3 groups. The diagnostic value of CEUS was assessed by receiver operating characteristic curves. Bayes discriminant analysis was adopted for building discriminant equations. Tm, De, Tm/De, Tep, and Iep/Iap were greater in patients with EVs (G1 and G2) than in those without EVs (G0). The Tms for the G0, G1, and G2 groups were 4.16 ± 0.59 mm, 7.06 ± 0.89 mm, and 10.10 ± 1.77 mm (P < 0.01), respectively, with 7.65 mm being the best cutoff value for diagnosing ≥ G2 (sensitivity 96.9%, specificity 90.0%). The area under the receiver operating characteristic curve was 0.987. Three discriminant equations were obtained by Bayes discriminant analysis: y 0 = −6.2 + 2.5Tm, y 1 = −15.1 + 4.1Tm and y 2 = −31.7 + 6.0Tm, respectively. The equations correctly classified 91.7% of cases in the study, making an error rate of 8.3%. Tm attained from CEUS can be a new, convenient, noninvasive parameter for evaluating esophageal varices in patients with liver cirrhosis.
Ultrasound Quarterly – Wolters Kluwer Health
Published: Jun 1, 2016
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