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PICTORIAL ESSAY:ABDOMINAL IMAGING Concurrent Focal Hepatic and Splenic Lesions A Pictorial Guide to Differential Diagnosis Marchelle J. Bean, MD, Karen M. Horton, MD, and Elliot K. Fishman, MD individuals, often because of tuberculosis, histoplasmosis, Abstract: Although medical literature and differential diagnoses Pneumocystis carinii, and disseminated bacterial and fungal discussions tend to be organ specific, systemic diseases more com- infections (Figs. 1, 2). monly manifest with multi-organ involvement. Detection of dual or- Computed tomography demonstrates multiple small ar- gan involvement combined with clinical history narrows the differ- eas of low attenuation, often with ring enhancement. Inter- ential to provide a more specific diagnosis. Two organs closely linked nally, the lesion may mimic a simple cyst or contain septations are the liver and the spleen. Many processes affect both of these or- and debris. The appearance of a host of infectious diseases and gans through their common denominator, the reticuloendothelial sys- metastatic deposits may have an identical imaging appearance, tem (RES). This pictorial essay reviews the wide spectrum of benign and malignant pathologies to be considered when computed tomog- with diagnosis resting on histologic sampling or response to raphy (CT) demonstrates concurrent focal disease in the liver and treatment. spleen. Key
Journal of Computer Assisted Tomography – Wolters Kluwer Health
Published: Sep 1, 2004
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