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ORIGINAL ARTICLE Computed Tomographic Perfusion Imaging for the Therapeutic Response of Chemoembolization for Hepatocellular Carcinoma Lin Yang, MD,*Þ Xiao-ming Zhang, MD,* Bang-xian Tan, MS,Þ Mi Liu, BS,Þ Guo-li Dong, MS,* and Zhao-hua Zhai, MS* ating method, which depended on the results of ultrasound, con- Background: Computed tomographic (CT) perfusion imaging has ventional computed tomography (CT), or magnetic resonance been applied in many clinical areas, but few studies have addressed the imaging, proposed to date, remains much debated, as tumors values of CT perfusion imaging in evaluating the therapeutic response may not decrease in size after chemoembolization despite their of chemoembolization for hepatocellular carcinoma (HCC). 7,8 being nonviable. The lack of accurate estimation of the thera- Objective: To assess the perfusion changes of HCC after transarterial peutic response of liver tumor has hindered the correct treatment chemoembolization, and to investigate the values of CT perfusion im- planning, such as the timing and frequency of repeat chemoem- aging in chemoembolization procedure. bolization, and it has also been difficult to evaluate the efficacy as Methods: Multidetector computed tomographic perfusion imaging was well as prognosis. Gratifyingly, an amendment to the RECIST, performed in 24 patients with HCC 1 week before and 4 weeks
Journal of Computer Assisted Tomography – Wolters Kluwer Health
Published: Mar 1, 2012
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