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Clinical Characteristics and Outcomes for Patients With Thymic Carcinoma Evaluation of Masaoka Staging

Clinical Characteristics and Outcomes for Patients With Thymic Carcinoma Evaluation of Masaoka... SPECIAL ARTICLE Clinical Characteristics and Outcomes for Patients With  Thymic Carcinoma Evaluation of Masaoka Staging Anya M. Litvak, MD,* Kaitlin Woo, MS,† Sara Hayes, MD,‡ James Huang, MD,§ Andreas Rimner, MD,║ Camelia S. Sima, MD, MS,† Andre L. Moreira, MD, PhD,¶ Maria Tsukazan, MD,§ and Gregory J. Riely, MD, PhD* hymic carcinomas are rare tumors, representing only 15% Background: Thymic carcinomas are rare cancers with limited data Tto 20% of all thymic neoplasms with fewer than 500 cases regarding outcomes, particularly for those patients with advanced 1,2 diagnosed in the United States per year. As such, most of disease. the literature on thymic carcinomas comes from retrospec- Methods: We identified patients with thymic carcinomas diagnosed tive reviews of surgical series, often from countries in Asia, between 1993 and 2012. Patient characteristics, recurrence-free sur- 3–16 where thymic carcinoma appears to be more prevalent. vival (RFS), and overall survival (OS) were analyzed. Data is limited regarding the clinical characteristics and clini- Results: One hundred twenty-one patients with thymic carcinomas cal behavior in a Western population, particularly in patients were identified. Higher Masaoka stage was associated with worse with advanced disease who are not surgical candidates. OS and RFS (5-year OS of 100%, 81%, 51%, 24%, and 17% for http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Clinical Characteristics and Outcomes for Patients With Thymic Carcinoma Evaluation of Masaoka Staging

Riely, Gregory J.
Journal of Thoracic Oncology , Volume 9 (12) – Dec 1, 2014
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Copyright © 2014 by the International Association for the Study of Lung Cancer
ISSN
1556-0864

Abstract

SPECIAL ARTICLE Clinical Characteristics and Outcomes for Patients With  Thymic Carcinoma Evaluation of Masaoka Staging Anya M. Litvak, MD,* Kaitlin Woo, MS,† Sara Hayes, MD,‡ James Huang, MD,§ Andreas Rimner, MD,║ Camelia S. Sima, MD, MS,† Andre L. Moreira, MD, PhD,¶ Maria Tsukazan, MD,§ and Gregory J. Riely, MD, PhD* hymic carcinomas are rare tumors, representing only 15% Background: Thymic carcinomas are rare cancers with limited data Tto 20% of all thymic neoplasms with fewer than 500 cases regarding outcomes, particularly for those patients with advanced 1,2 diagnosed in the United States per year. As such, most of disease. the literature on thymic carcinomas comes from retrospec- Methods: We identified patients with thymic carcinomas diagnosed tive reviews of surgical series, often from countries in Asia, between 1993 and 2012. Patient characteristics, recurrence-free sur- 3–16 where thymic carcinoma appears to be more prevalent. vival (RFS), and overall survival (OS) were analyzed. Data is limited regarding the clinical characteristics and clini- Results: One hundred twenty-one patients with thymic carcinomas cal behavior in a Western population, particularly in patients were identified. Higher Masaoka stage was associated with worse with advanced disease who are not surgical candidates. OS and RFS (5-year OS of 100%, 81%, 51%, 24%, and 17% for

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Dec 1, 2014

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