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CD3δ immunodeficiency

CD3δ immunodeficiency Unlike patients with CD3γ or CD3ε deficiency who have a milder condition, patients with CD3δ deficiency present with severe lethal susceptibility to infections during early infancy. As expected, this profound immunodeficiency was cured with an allogenic bone marrow transplantation. In contrast to murine CD3δ http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Allergy and Clinical Immunology Wolters Kluwer Health

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Copyright
Copyright © 2004 by Lippincott Williams & Wilkins. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise without either the prior written permission of the Publisher or a licence permitting restricted copying issued in the UK by the Copyright Licensing Authority and in the USA by the Copyright Clearance Center. Applications for permission should be addressed to the International Rights Department, Lippincott Williams & Wilkins, 227 East Washington Square, Philadelphia, PA 19106-380, USA, or faxed to (+1) 215 238 4419. 1528-4050/04.
ISSN
1528-4050
eISSN
1473-6322

Abstract

Unlike patients with CD3γ or CD3ε deficiency who have a milder condition, patients with CD3δ deficiency present with severe lethal susceptibility to infections during early infancy. As expected, this profound immunodeficiency was cured with an allogenic bone marrow transplantation. In contrast to murine CD3δ

Journal

Current Opinion in Allergy and Clinical ImmunologyWolters Kluwer Health

Published: Dec 1, 2004

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