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ORIGINAL ARTICLE Cannabis Smoking and Risk of Lung Cancer in Men A Pooled Analysis of Three Studies in Maghreb Julien Berthiller, MSc,*† Kurt Straif, MD, PhD,* Mathieu Boniol, PhD,* Nicolas Voirin, MSc,‡§ Veronique Benhaïm-Luzon, AA,* Wided Ben Ayoub, MD, Iman Dari, MD,¶ Slimane Laouamri, MD,# Mokhtar Hamdi-Cherif, MD, PhD,# Mohamed Bartal, MD, PhD,¶ Fahrat Ben Ayed, MD, PhD, and Annie J. Sasco, MD, PhD** tobacco smoking or other potential confounders may explain part of Background: Cannabis is the most widely consumed illicit drug the increased risk. worldwide and the relation between cannabis smoking and lung Key Words: Cannabis, Lung cancer, Maghreb, Tobacco, Pooled cancer is suggestive, albeit inconclusive. case-control study. Method: We conducted three hospital based case-control studies in Tunisia, Morocco, and Algeria, three areas of high prevalence of (J Thorac Oncol. 2008;3: 1398 –1403) cannabis consumption as well as production. This paper presents the pooled analysis of these three studies restricted to men with a total of 430 cases and 778 controls. ith 1.18 million deaths in 2002, lung cancer is the Results: Ninety-six percent of the cases and 67.8% of the controls Wleading cause of cancer deaths among men. In 2002, were tobacco smokers and 15.3% of
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Dec 1, 2008
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