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Journal of Medical Microbiology (2015), 64, 199–208 DOI 10.1099/jmm.0.078717-0 Candida biofilm formation on voice prostheses Review 1 2 3 4 Moira J. Talpaert, Alistair Balfour, Sarah Stevens, Mark Baker, 1,4 1 Fritz A. Muhlschlegel and Campbell W. Gourlay Correspondence Kent Fungal Group, School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK Fritz A. Muhlschlegel Ear, Nose and Throat Services, East Kent Hospitals University NHS Foundation Trust, F.A.Muhlschlegel@kent.ac.uk The William Harvey Hospital, Kennington Road, Ashford TN24 0LZ, UK Campbell W. Gourlay Macmillan Speech and Language Therapy Services, Kent and Canterbury Hospital, Ethelbert Road, C.W.Gourlay@kent.ac.uk Canterbury CT1 3NG, UK Clinical Microbiology Service, East Kent Hospitals University NHS Foundation Trust, The William Harvey Hospital, Kennington Road, Ashford TN24 0LZ, UK Laryngopharyngeal malignancy is treated with radiotherapy and/or surgery. When total laryngectomy is required, major laryngeal functions (phonation, airway control, swallowing and coughing) are affected. The insertion of a silicone rubber voice prosthesis in a surgically created tracheoesophageal puncture is the most effective method for voice rehabilitation. Silicone, as is the case with other synthetic materials such as polymethylmethacrylate, polyurethane, polyvinyl chloride, polypropylene and polystyrene, has the propensity to become rapidly colonized by micro-organisms (mainly Candida albicans) forming a biofilm, which leads
Journal of Medical Microbiology – Wolters Kluwer Health
Published: Mar 1, 2015
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