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Calponin is Expressed in Serous Cystadenomas of the Pancreas but not in Adenocarcinomas or Endocrine Tumors

Calponin is Expressed in Serous Cystadenomas of the Pancreas but not in Adenocarcinomas or... Downloaded from http://journals.lww.com/appliedimmunohist by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/10/2020 RESEARCH ARTICLE Calponin is Expressed in Serous Cystadenomas of the Pancreas but not in Adenocarcinomas or Endocrine Tumors William L. Marsh, MD,* Jorge Colonna, MD,* Martha Yearsley, MD,* Mark Bloomston, MD,w and Wendy L. Frankel, MD* ancreatic serous cystic neoplasms, which are almost Abstract: The diagnosis of serous microcystic adenoma (SMA) is Palways benign, were first clearly separated from usually straightforward. For small biopsies and/or unusual pancreatic mucinous cystic neoplasms, which have the 1,2 variants, the differential diagnosis includes other pancreatic or potential to behave aggressively, in the year 1978. metastatic neoplasms showing cystic or clear cell features. We Serous cystic neoplasms constitute approximately 5% to evaluated immunostains for potential use in the diagnosis of 15% of all cystic lesions of the pancreas and approxi- SMA. Cases of SMA were identified from archival files. Tissue mately 25% of all cystic neoplasms of the pancreas. cores (2 per block) were arrayed to create a microarray of cores Serous microcystic adenomas (SMAs) comprise >90% measuring 2 mm each. Additionally, microarrays previously of pancreatic serous cystic neoplasms with the remainder constructed from 56 pancreatic adenocarcinomas (PACs) and 64 classified predominantly as serous oligocystic (macrocys- 1–12 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Immunohistochemistry & Molecular Morphology Wolters Kluwer Health

Calponin is Expressed in Serous Cystadenomas of the Pancreas but not in Adenocarcinomas or Endocrine Tumors

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Publisher
Wolters Kluwer Health
ISSN
1541-2016
DOI
10.1097/PAI.0b013e31818c1aa6
Publisher site
See Article on Publisher Site

Abstract

Downloaded from http://journals.lww.com/appliedimmunohist by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/10/2020 RESEARCH ARTICLE Calponin is Expressed in Serous Cystadenomas of the Pancreas but not in Adenocarcinomas or Endocrine Tumors William L. Marsh, MD,* Jorge Colonna, MD,* Martha Yearsley, MD,* Mark Bloomston, MD,w and Wendy L. Frankel, MD* ancreatic serous cystic neoplasms, which are almost Abstract: The diagnosis of serous microcystic adenoma (SMA) is Palways benign, were first clearly separated from usually straightforward. For small biopsies and/or unusual pancreatic mucinous cystic neoplasms, which have the 1,2 variants, the differential diagnosis includes other pancreatic or potential to behave aggressively, in the year 1978. metastatic neoplasms showing cystic or clear cell features. We Serous cystic neoplasms constitute approximately 5% to evaluated immunostains for potential use in the diagnosis of 15% of all cystic lesions of the pancreas and approxi- SMA. Cases of SMA were identified from archival files. Tissue mately 25% of all cystic neoplasms of the pancreas. cores (2 per block) were arrayed to create a microarray of cores Serous microcystic adenomas (SMAs) comprise >90% measuring 2 mm each. Additionally, microarrays previously of pancreatic serous cystic neoplasms with the remainder constructed from 56 pancreatic adenocarcinomas (PACs) and 64 classified predominantly as serous oligocystic (macrocys- 1–12

Journal

Applied Immunohistochemistry & Molecular MorphologyWolters Kluwer Health

Published: May 1, 2009

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