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Blood Glucose and Atherosclerosis

Blood Glucose and Atherosclerosis Review Robert W. Stout he relationship of diabetes to cardiovascular T disease has been known for over half a cen- Atherosclerosis and Diabetes tury and has been the subject of a number of Autopsy Evidence reviews. The topic was discussed by the author Epidemiological Evidence—The Framingham and two colleagues in 1975, and the present paper concentrates on information published Study since that time. Blood Glucose and Arterial Disease Although it is well known that diabetic patients commonly die from cardiovascular disease and Risk Factors for Atherosclerosis in Diabetes that cardiovascular disease is particularly common in diabetes, a number of questions Nonatherosclerotic Heart Disease in Diabetes remain unanswered. It is now clear that diabetes mellitus consists of at least two distinct disorders Other Factors Associated with Atherosclerosis that differ both genetically and in their metabolic and Diabetes abnormalities. The majority of diabetics have Insulin and Atherosclerosis Type II, or noninsulin-dependent, diabetes melli- tus (NIDDM), characterized by mild to moderate Chlorpropamide-Alcohol Flushing and Vascular glucose intolerance, a high frequency of obesity, Disease in Noninsulin-Dependent Diabetes absence of a tendency to ketoacidosis, and re- Conclusions sponse to treatment with diet or oral antidiabetic drugs. A minority (20%) of diabetics have Type I, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis Wolters Kluwer Health

Blood Glucose and Atherosclerosis

Arteriosclerosis , Volume 1 (4) – Jul 1, 1981

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Copyright
© 1981 by American Heart Association, Inc.
ISSN
0276-5047

Abstract

Review Robert W. Stout he relationship of diabetes to cardiovascular T disease has been known for over half a cen- Atherosclerosis and Diabetes tury and has been the subject of a number of Autopsy Evidence reviews. The topic was discussed by the author Epidemiological Evidence—The Framingham and two colleagues in 1975, and the present paper concentrates on information published Study since that time. Blood Glucose and Arterial Disease Although it is well known that diabetic patients commonly die from cardiovascular disease and Risk Factors for Atherosclerosis in Diabetes that cardiovascular disease is particularly common in diabetes, a number of questions Nonatherosclerotic Heart Disease in Diabetes remain unanswered. It is now clear that diabetes mellitus consists of at least two distinct disorders Other Factors Associated with Atherosclerosis that differ both genetically and in their metabolic and Diabetes abnormalities. The majority of diabetics have Insulin and Atherosclerosis Type II, or noninsulin-dependent, diabetes melli- tus (NIDDM), characterized by mild to moderate Chlorpropamide-Alcohol Flushing and Vascular glucose intolerance, a high frequency of obesity, Disease in Noninsulin-Dependent Diabetes absence of a tendency to ketoacidosis, and re- Conclusions sponse to treatment with diet or oral antidiabetic drugs. A minority (20%) of diabetics have Type I,

Journal

ArteriosclerosisWolters Kluwer Health

Published: Jul 1, 1981

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