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EDITORIAL a b c d Jens D. Lundgren , John Baxter , Steven G. Deeks and H. Clifford Lane National University Hospital, University of Copenhagen, Copenhagen, Denmark, measure. Often the challenge is having an adequate repo- Cooper University Hospital/UMDNJ-Robert Wood Johnson Medical School, sitory of correctly stored biological samples linked with a Camden, New Jersey, Department of Medicine, University of California, San Francisco, California and National Institute of Allergy and Infectious Diseases, database of quality-assured clinical and therapeutic infor- National Institutes of Health, Bethesda, Maryland, USA mation to be able to address the research question in a Correspondence to H. Clifford Lane, CRC Room 4-1479, National Institutes of robust manner. A good biomarker study is often dependent Health, Bethesda, MD 20892, USA upon a careful prospective plan for the collection and E-mail: clane@nih.gov storage of biological samples. Huppler-Hullsiek and col- Current Opinion in HIV and AIDS 2010, 5:459–462 leagues describe their extensive experience in the creation of appropriate biobanks linked with clinical trials. The Introduction statistical analyses of biomarker databases are also a chal- As noted by Stimbu and Tavel in their introductory lenging field and are comprehensively reviewed by Grund paper, the term biomarker is a combination of
Current Opinion in HIV and Aids – Wolters Kluwer Health
Published: Nov 1, 2010
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