Access the full text.
Sign up today, get DeepDyve free for 14 days.
References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.
Li Wu Department of Microbiology and Molecular Genetics, Purpose of review Medical College of Wisconsin, Milwaukee, Wisconsin, HIV-1 mucosal transmission plays a critical role in HIV-1 infection and AIDS USA pathogenesis. This review summarizes the latest advances in biological studies of HIV-1 Correspondence to Li Wu, Department of Microbiology mucosal transmission, highlighting the implications of these studies in the development and Molecular Genetics, BSB 203, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, of microbicides to prevent HIV-1 transmission. WI 53226, USA Recent findings Tel: +1 414 456 4075; fax: +1 414 456 6535; e-mail: liwu@mcw.edu New studies of initial HIV-1 infection using improved culture models updated the current view of mucosal transmission. Mechanistic studies enhanced our understanding of cell – cell transmission of HIV-1 mediated by the major target cells, including dendritic Current Opinion in HIV and AIDS 2008, 3:534– cells, CD4 T cells, and macrophages. Increasing evidence indicated the significance of host factors and immune responses in HIV-1 mucosal infection and transmission. Summary Recent progress in HIV-1 mucosal infection and transmission enriches our knowledge of virus – host interactions and viral pathogenesis. Functional studies of HIV-1 interactions with host cells can provide new insights into the
Current Opinion in HIV and Aids – Wolters Kluwer Health
Published: Sep 1, 2008
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.