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V. Ziller, M. Kalder, U. Albert, W. Holzhauer, M. Ziller, U. Wagner, P. Hadji (2008)
Adherence to adjuvant endocrine therapy in postmenopausal women with breast cancer.Annals of oncology : official journal of the European Society for Medical Oncology, 20 3
M. Banning (2012)
Adherence to adjuvant therapy in post-menopausal breast cancer patients: a review.European journal of cancer care, 21 1
L. Osterberg, T. Blaschke (2005)
Adherence to medication.The New England journal of medicine, 353 5
A. Partridge, Philip Wang, E. Winer, J. Avorn (2003)
Nonadherence to adjuvant tamoxifen therapy in women with primary breast cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 21 4
Heather McDonald, Amit Garg, R. Haynes (2002)
Interventions to enhance patient adherence to medication prescriptions: scientific review.JAMA, 288 22
A. Howell, J. Cuzick, M. Baum, A. Buzdar, M. Dowsett, J. Forbes, G. Hoctin-Boes, J. Houghton, G. Locker, J. Tobias (2005)
Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancerThe Lancet, 365
Christopher Truffer, Sean Keehan, Sheila Smith, J. Cylus, Andrea Sisko, J. Poisal, Joseph Lizonitz, M. Clemens (2010)
Health spending projections through 2019: the recession's impact continues.Health affairs, 29 3
H. Mouridsen, A. Giobbie-Hurder, A. Goldhirsch, B. Thürlimann, R. Paridaens, I. Smith, L. Mauriac, J. Forbes, K. Price, M. Regan, R. Gelber, A. Coates (2009)
Letrozole therapy alone or in sequence with tamoxifen in women with breast cancer.The New England journal of medicine, 361 8
D. Hershman, T. Shao, L. Kushi, D. Buono, W. Tsai, L. Fehrenbacher, M. Kwan, S. Gomez, A. Neugut (2011)
Early discontinuation and non-adherence to adjuvant hormonal therapy are associated with increased mortality in women with breast cancerBreast Cancer Research and Treatment, 126
A. Lintermans, P. Neven (2011)
Pharmacology of arthralgia with estrogen deprivationSteroids, 76
C. Presant, L. Bosserman, T. Young, M. Vakil, R. Horns, G. Upadhyaya, B. Ebrahimi, C. Yeon, F. Howard (2007)
Aromatase inhibitor-associated arthralgia and/ or bone pain: frequency and characterization in non-clinical trial patients.Clinical breast cancer, 7 10
N. Henry, J. Giles, D. Ang, M. Mohan, Dina Dadabhoy, J. Robarge, J. Hayden, S. Lemler, K. Shahverdi, P. Powers, Lang Li, D. Flockhart, V. Stearns, D. Hayes, A. Storniolo, D. Clauw (2008)
Prospective characterization of musculoskeletal symptoms in early stage breast cancer patients treated with aromatase inhibitorsBreast Cancer Research and Treatment, 111
V. Ziller, I. Kyvernitakis, D. Knöll, A. Storch, O. Hars, P. Hadji (2013)
Influence of a patient information program on adherence and persistence with an aromatase inhibitor in breast cancer treatment - the COMPAS studyBMC Cancer, 13
Cuzick J, Sestak I, Baum M
Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial
E. Fromme, K. Eilers, M. Mori, Y. Hsieh, T. Beer (2004)
How accurate is clinician reporting of chemotherapy adverse effects? A comparison with patient-reported symptoms from the Quality-of-Life Questionnaire C30.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 22 17
E. Basch, A. Deal, M. Kris, H. Scher, C. Hudis, P. Sabbatini, L. Rogak, A. Bennett, A. Dueck, T. Atkinson, J. Chou, Dorothy Dulko, L. Sit, A. Barz, P. Novotny, M. Fruscione, J. Sloan, D. Schrag (2016)
Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 34 6
R. Coombes, L. Kilburn, C. Snowdon, R. Paridaens, R. Coleman, Stephen Jones, J. Jassem, C. Velde, T. Delozier, I. Álvarez, L. Mastro, O. Ortmann, K. Diedrich, A. Coates, E. Bajetta, S. Holmberg, D. Dodwell, E. Mickiewicz, J. Andersen, P. Lønning, G. Cocconi, J. Forbes, M. Castiglione, N. Stuart, A. Stewart, L. Fallowfield, G. Bertelli, E. Hall, R. Bogle, M. Carpentieri, E. Colajori, M. Subar, E. Ireland, J. Bliss (2007)
Survival and safety of exemestane versus tamoxifen after 2–3 years' tamoxifen treatment (Intergroup Exemestane Study): a randomised controlled trialThe Lancet, 369
L. Fallowfield, J. Bliss, L. Porter, M. Price, C. Snowdon, Stephen Jones, R. Coombes, E. Hall (2006)
Quality of life in the intergroup exemestane study: a randomized trial of exemestane versus continued tamoxifen after 2 to 3 years of tamoxifen in postmenopausal women with primary breast cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 6
M. Baum, A. Budzar, J. Cuzick, J. Forbes, J. Houghton, J. Klijn, T. Sahmoud (2002)
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trialThe Lancet, 359
S. Gaillard, V. Stearns (2011)
Aromatase inhibitor-associated bone and musculoskeletal effects: new evidence defining etiology and strategies for managementBreast Cancer Research : BCR, 13
National Comprehensive Cancer Network
NCCN clinical practice guidelines in oncology: Breast cancer, version 2
C. Owusu, D. Buist, T. Field, T. Lash, S. Thwin, A. Geiger, V. Quinn, F. Frost, M. Prout, M. Yood, F. Wei, R. Silliman (2008)
Predictors of tamoxifen discontinuation among older women with estrogen receptor-positive breast cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26 4
S. Karve, M. Cleves, M. Helm, T. Hudson, D. West, B. Martin (2009)
Good and poor adherence: optimal cut-point for adherence measures using administrative claims dataCurrent Medical Research and Opinion, 25
A. Partridge, Andrea LaFountain, E. Mayer, B. Taylor, E. Winer, A. Asnis-Alibozek (2008)
Adherence to initial adjuvant anastrozole therapy among women with early-stage breast cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26 4
D. Hershman, Jennifer Tsui, Jay Meyer, S. Glied, G. Hillyer, J. Wright, A. Neugut (2014)
The change from brand-name to generic aromatase inhibitors and hormone therapy adherence for early-stage breast cancer.Journal of the National Cancer Institute, 106 11
D. Hershman, L. Kushi, T. Shao, D. Buono, A. Kershenbaum, W. Tsai, L. Fehrenbacher, S. Gomez, Sunita Miles, A. Neugut (2010)
Early discontinuation and nonadherence to adjuvant hormonal therapy in a cohort of 8,769 early-stage breast cancer patients.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 28 27
A. Neugut, A. Neugut, G. Hillyer, L. Kushi, L. Lamerato, Nicole Leoce, S. Nathanson, C. Ambrosone, D. Bovbjerg, J. Mandelblatt, C. Magai, W. Tsai, J. Jacobson, D. Hershman (2012)
Non-initiation of adjuvant hormonal therapy in women with hormone receptor-positive breast cancer: The Breast Cancer Quality of Care Study (BQUAL)Breast Cancer Research and Treatment, 134
C. McCowan, J. Shearer, P. Donnan, J. Dewar, M. Crilly, A. Thompson, T. Fahey, T. Fahey (2008)
Cohort study examining tamoxifen adherence and its relationship to mortality in women with breast cancerBritish Journal of Cancer, 99
M. Maio, C. Gallo, N. Leighl, M. Piccirillo, G. Daniele, F. Nuzzo, C. Gridelli, V. Gebbia, F. Ciardiello, S. Placido, A. Ceribelli, A. Favaretto, A. Matteis, R. Feld, C. Butts, J. Bryce, S. Signoriello, A. Morabito, G. Rocco, F. Perrone (2015)
Symptomatic toxicities experienced during anticancer treatment: agreement between patient and physician reporting in three randomized trials.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33 8
T. Barron, C. Cahir, L. Sharp, Kathleen Bennett (2013)
A nested case–control study of adjuvant hormonal therapy persistence and compliance, and early breast cancer recurrence in women with stage I–III breast cancerBritish Journal of Cancer, 109
P. Hadji, M. Blettner, N. Harbeck, C. Jackisch, H. Lück, C. Windemuth-Kieselbach, S. Zaun, R. Kreienberg (2013)
The Patient's Anastrozole Compliance to Therapy (PACT) Program: a randomized, in-practice study on the impact of a standardized information program on persistence and compliance to adjuvant endocrine therapy in postmenopausal women with early breast cancer.Annals of oncology : official journal of the European Society for Medical Oncology, 24 6
J. Mao, C. Stricker, D. Bruner, S. Xie, M. Bowman, J. Farrar, Brandon Greene, A. DeMichele (2009)
Patterns and risk factors associated with aromatase inhibitor‐related arthralgia among breast cancer survivorsCancer, 115
D. Hershman, Jennifer Tsui, J. Wright, E. Coromilas, W. Tsai, A. Neugut (2015)
Household net worth, racial disparities, and hormonal therapy adherence among women with early-stage breast cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33 9
O. Abe, R. Abe, K. Enomoto, K. Kikuchi, H. Koyama, H. Masuda, Y. Nomura, K. Sakai, K. Sugimachi, T. Tominaga, J. Uchino, M. Yoshida, J. Haybittle, C. Davies, V. Harvey, TM Holdaway, R. Kay, B. Mason, J. Forbes, N. Wilcken, M. Gnant, R. Jakesz, M. Ploner, H. Yosef, C. Focan, J. Lobelle, U. Peek, G. Oates, J. Powell, M. Durand, L. Mauriac, A. Leo, S. Dolci, M. Piccart, M. Masood, D. Parker, J. Price, P. Hupperets, S. Jackson, J. Ragaz, D. Berry, G. Broadwater, C. Cirrincione, H. Muss, L. Norton, R. Weiss, H. Abu‐Zahra, S. Portnoj, M. Baum, J. Cuzick, J. Houghton, D. Riley, NH Gordon, H. Davis, A. Beatrice, J. Mihura, A. Naja, Y. Lehingue, P. Romestaing, JB Dubois, T. Delozier, J. Macé-Lesec’h, P. Rambert, O. Andrysek, J. Barkmanova, Owen, P. Meier, A. Howell, G. Ribeiro, R. Swindell, R. Alison, J. Boreham, M. Clarke, R. Collins, S. Darby, P. Elphinstone, Evans, J. Godwin, R. Gray, C. Harwood, C. Hicks, S. James, E. Mackinnon, P. Mcgale, T. McHugh, G. Mead, R. Peto, Y. Wang, J. Albano, Cf Oliveira, H. Gervásio, J. Gordilho, H. Johansen, H. Mouridsen, R. Gelman, Harris, I. Henderson, Claire Shapiro, K. Andersen, C. Axelsson, M. Blichert‐Toft, S. Møller, J. Overgaard, M. Overgaard, C. Rose, B. Cartensen, T. Palshof, H. Trampisch, O. Dalesio, D. Vries, S. Rodenhuis, H. Tinteren, R. Comis, N. Davidson, N. Robert, G. Sledge, D. Tormey, W. Wood, D. Cameron, U. Chetty, P. Forrest, W. Jack, J. Rossbach, J. Klijn, A. Treurniet‐Donker, W. Putten, Alberto Costa, U. Veronesi, H. Bartelink, L. Duchateau, C. Legrand, R. Sylvester, J. Hage, C. Velde, M. Cunningham, R. Catalano, R. Creech, J. Bonneterre, P. Fargeot, P. Fumoleau, P. Kerbrat, M. Namer, W. Jonat, M. Kaufmann, M. Schumacher, G. Minckwitz, G. Bastert, H. Rauschecker, R. Sauer, W. Sauerbrei, A. Schauer, A. Schryver, L. Vakaet, M. Belfiglio, A. Nicolucci, F. Pellegrini, M. Sacco, M. Valentini, C. McArdle, D. Smith, E. Galligioni, F. Boccardo, A. Rubagotti, D. Dent, C. Gudgeon, A. Hacking, A. Erazo, J. Medina, M. Izuo, Y. Morishita, H. Takei, I. Fentiman, J. Hayward, R. Rubens, D. Skilton, H. Graeff, F. Jänicke, C. Meisner, H. Scheurlen, D. Fournier, U. Dafni, G. Fountzilas, P. Klefstrom, C. Blomqvist, T. Saarto, R. Margreiter, B. Asselain, R. Salmon, Vilcoq, R. Arriagada, C. Hill, A. Laplanche, M. Lê, M. Spielmann, P. Bruzzi, E. Montanaro, R. Rosso, Sertoli, M. Venturini, D. Amadori, J. Benraadt, M. Kooi, A. Velde, J. Dongen, J. Vermorken, M. Castiglione, F. Cavalli, A. Coates, J. Collins, J. Forbes, R. Gelber, A. Goldhirsch, J. Lindtner, K. Price, C. Rudenstam, H. Senn, J. Bliss, C. Chilvers, R. Coombes, E. Hall, M. Marty, R. Borovik, G. Brufman, H. Hayat, E. Robinson, N. Wigler, G. Bonadonna, T. Camerini, G. Palo, M. Vecchio, F. Formelli, P. Valagussa, A. Martoni, F. Pannuti, G. Cocconi, A. Colozza, R. Camisa, K. Aogi, S. Takashima, T. Ikeda, K. Inokuchi, K. Sawa, H. Sonoo, S. Korzeniowski, J. Skołyszewski, M. Ogawa, J. Yamashita, J. Bonté, R. Christiaens, R. Paridaens, W. Boegart, P. Martin, S. Romain, T. Hakes, C. Hudis, R. Wittes, G. Giokas, D. Kondylis, B. Lissaios, R. Huerta, MG Sainz, R. Altemus, K. Cowan, D. Danforth, A. Lichter, M. Lippman, J. O’Shaughnessy, L. Pierce, S. Steinberg, D. Venzon, J. Zujewski, A. Paradiso, M. Lena, F. Schittulli, J. Myles, J. Pater, K. Pritchard, S. Anderson, G. Bass, Andrew Brown, J. Bryant, J. Costantino, J. Dignam, B. Fisher, C. Redmond, S. Wieand, N. Wolmark, I. Jackson, M. Palmer, J. Ingle, V. Suman, N. Bengtsson, H. Jonsson, L. Larsson, J. Lythgoe, M. Kissin, B. Erikstein, E. Hannisdal, Abby Jacobsen, J. Varhaug, S. Gundersen, M. Hauer-Jensen, H. Høst, R. Nissen-Meyer, R. Blamey, A. Mitchell, D. Morgan, J. Robertson, M. Palma, G. Mathé, J. Misset, R. Clark, M. Levine, K. Morimoto, Y. Takatsuka, E. Crossley, A. Harris, D. Talbot, Marianne Taylor, B. Blasio, Ivanov, Semiglazov, J. Brockschmidt, Cooper, H. Ueo, C. Falkson, R. a'Hern, S. Ashley, T. Powles, I. Smith, Yarnold, Gazet Jc, N. Cocoran, N. Deshpande, L. Martino, P. Douglas, A. Lindtner, G. Notter, Ajs Bryant, G. Ewing, L. Firth, J. Krushen-Kosloski, L. Foster, W. George, H. Stewart, P. Stroner, P. Malmström, T. Möller, S. Rydén, Tengrup, L. Tennvall-Nittby, J. Carstenssen, M. Dufmats, T. Hatschek, B. Nordenskjöld, M. Söderberg, J. Carpenter, K. Albain, James Crowley, S. Green, S. Martino, C. Osborne, P. Ravdin, U. Glas, U. Johansson, L. Rutqvist, T. Singnomklao, A. Wallgren, R. Maibach, B. Thürlimann, H. Brenner, A. Hercbergs, M. Yoshimoto, G. Deboer, A. Paterson, J. Meakin, T. Panzarella, Y. Shan, Y. Shao, Y Wang, DB Zhao, Zm Chen, HC Pan, J. Bahi, M. Reid, M. Spittle, Gp Deutsch, F. Senanayake, D. Kwong, A. Bianco, C. Carlomagno, M. Laurentiis, S. Placido, A. Buzdar, Thomas Smith, J. Bergh, L. Holmberg, G. Liljegren, J. Nilsson, M. Seifert, P. Sevelda, C. Zielinsky, R. Buchanan, M. Cross, G. Royle, J. Dunn, R. Hills, M. Lee, J. Morrison, D. Spooner, A. Litton, R. Chlebowski, H. Caffier, Ebctcg (2005)
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trialsThe Lancet, 365
D. Geynisman, K. Wickersham (2013)
Adherence to targeted oral anticancer medications.Discovery medicine, 15 83
Fromme EK, Eilers KM, Mori M
How accurate is clinician reporting of chemotherapy adverse effects
Introduction: Up to 40% of patients with breast cancer may not adhere to adjuvant endocrine therapy. Therapy-related adverse effects (AEs) are important contributors to nonadherence. We developed a bidirectional text-message application, BETA-Text, that simultaneously tracks adherence, records symptoms, and alerts the clinical team. Patients and Methods: We piloted our intervention in 100 patients. The intervention consisted of text messages to which patients responded for 3 months: daily, evaluating adherence; weekly, evaluating medication-related AEs; and monthly, regarding barriers to adherence. Concerning responses prompted a telephone call from a clinic nurse. The primary objective was to assess patient acceptance of this intervention using self-reported surveys. To compare participants with the general population at our institution, we assessed 100 consecutively treated patients as historical controls using medical record review. Results: We approached 141 consecutive patients, 100 (71%) of whom agreed to participate and 89 of whom completed the intervention. A majority of patients reported that the intervention was easy to use (98%) and helpful in taking their medication (96%). Four patients discontinued therapy before 3 months, and 93% of patients who continued therapy took >= 80% of their medication. The frequency of AEs reported by participants via text was higher than that reported in clinical trials: hot flashes (72%), arthralgias (53%), and vaginal symptoms (35%). Approximately 39% of patients reported one or more severe AE that prompted an alert to the provider team to call the patient. Conclusion: A daily bidirectional text-messaging system can monitor adherence and identify AEs and other barriers to adherence in real time without inconveniencing patients. AEs of endocrine therapy, as detected using this texting approach, are more prevalent than reported in clinical trials.
JCO Clinical Cancer Informatics – Wolters Kluwer Health
Published: May 23, 2017
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