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A. Levene (1980)
Diagnostic Electron Microscopy of Tumours.Journal of the Royal Society of Medicine, 73
F. Leong, A. Leong (2003)
Digital Imaging Applications in Anatomic PathologyAdvances in Anatomic Pathology, 10
A. Leong, K. Cooper, F. Leong (1998)
Manual of Diagnostic Antibodies for Immunohistology
Y. Cam, G. Bellon, G. Poulin, Y. Caron, P. Birembaut (1984)
Distribution of type IV collagen in benign and malignant epithelial proliferations. An indirect immunofluorescence study on the breasts, the lungs, and the skin.Invasion & metastasis, 4 2
W. Raymond, A. Leong (1991)
Assessment of invasion in breast lesions using antibodies to basement membrane components and myoepithelial cellsPathology, 23
P. Birembaut, Y. Caron, J. Adnet, J. Foidart (1985)
Usefulness of basement membrane markers in tumoural pathologyThe Journal of Pathology, 145
A. Leong, S. Vinyuvat, C. Suthipintawong, F. Leong (1997)
Patterns of Basal Lamina Immunostaining in Soft-Tissue and Bony Tumors, 5
C. Fermin, S. DeGraw (1995)
Colour thresholding in video imaging.Journal of anatomy, 186 ( Pt 3)
A. Leong (1993)
Applied immunohistochemistry for the surgical pathologist
(2005)
An automated diagnostic system for tubular carcinoma of the breast: a model for computer-based cancer diagnosis
K. Castleman (1998)
Concepts in imaging and microscopy: color image processing for microscopy.The Biological bulletin, 194 2
Jeroen Laak, M. Pahlplatz, Antonius Hanselaar, Peter Wilde (2000)
Hue-saturation-density (HSD) model for stain recognition in digital images from transmitted light microscopy.Cytometry, 39 4
A. Leong, J. Wright (1987)
The contribution of immunohistochemical staining in tumour diagnosisHistopathology, 11
TECHNICAL Basal Lamina Visualization Using Color Image Processing and Pattern Recognition F. Joel W.-M. Leong, MD, PhD (Oxon),* Anthony S.-Y. Leong, MB, MD, FRCPA, FRCPath, FCAP, FASCP, FHKAM (Pathol), Hon FHKCPath, Hon FRCPath (Thailand),† Michael Brady, FRS, FREng, FIEE, FInstP, FAAAI,‡ and James O’D. McGee, MD, PhD, FRCPG, MA, FMedSci§ tent. It also contains non-collagenous glycoproteins such as Abstract: In histologic assessment, the absence of basal lamina is laminin, fibronectin, heparin sulfate, proteoglycan, entactin, a useful feature for distinguishing invasive malignancy from benign This barrier of fibronectin, and other glycosaminoglycans. and in situ lesions. As this feature is not possible to assess in routine granulofilamentous polysaccharide-rich material with associ- H&E sections, pathologists have instead relied on histochemical and ated collagen fibrils is present at the base of epithelium and immunohistochemical stains to show components of the basal lam- around benign glands but is generally absent around the ma- ina such as laminin or type IV collagen. Standard image-processing lignant glands of invasive carcinoma. The basal lamina has software with the necessary image-processing toolbox (Matlab v5, been examined in isolation, on the basis that it forms a sig- Mathworks, Natick, MA) was used in a unique combination of color nificant
Applied Immunohistochemistry & Molecular Morphology – Wolters Kluwer Health
Published: Sep 1, 2005
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