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Atrophic rhinosinusitis: progress toward explanation of an unsolved medical mystery

Atrophic rhinosinusitis: progress toward explanation of an unsolved medical mystery Atrophic rhinosinusitis: progress toward explanation of an unsolved medical mystery a b Richard D. deShazo and Scott P. Stringer Department of Medicine, Division of Clinical Allergy Purpose of review and Immunology and Department of Otarlaryngology, Atrophic rhinosinusitis is a chronic condition associated with considerable morbidity University of Mississippi Medical Center, Jackson, Mississippi, USA and decreased quality of life. This review describes progress in the characterization of primary and secondary atrophic rhinosinusitis and the development of diagnostic criteria Correspondence to Richard D. deShazo, MD, Department of Medicine, University of Mississippi for both syndromes. Medical Center, 2500 N. State Street, Jackson, MS Recent findings 39216-4505, USA E-mail: rdeshazo@umc.edu Primary atrophic rhinitis usually develops as a consequence of an acute febrile illness in members of lower socioeconomic groups in developing areas of the world. The clinical Current Opinion in Allergy and Clinical Immunology 2011, 11:1–7 setting and presence of culturable Klebsialla ozenae in the purulent, foul-smelling, nasal discharge of these patients forms the basis for diagnosis. An animal model for the disease exists in swine in which case an effective vaccine has been developed. Secondary atrophic rhinosinusitis is a condition that follows destruction of the nasal mucosa by any of a number http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Allergy and Clinical Immunology Wolters Kluwer Health

Atrophic rhinosinusitis: progress toward explanation of an unsolved medical mystery

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ISSN
1528-4050
eISSN
1473-6322
DOI
10.1097/ACI.0b013e328342333e
pmid
21157302
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Abstract

Atrophic rhinosinusitis: progress toward explanation of an unsolved medical mystery a b Richard D. deShazo and Scott P. Stringer Department of Medicine, Division of Clinical Allergy Purpose of review and Immunology and Department of Otarlaryngology, Atrophic rhinosinusitis is a chronic condition associated with considerable morbidity University of Mississippi Medical Center, Jackson, Mississippi, USA and decreased quality of life. This review describes progress in the characterization of primary and secondary atrophic rhinosinusitis and the development of diagnostic criteria Correspondence to Richard D. deShazo, MD, Department of Medicine, University of Mississippi for both syndromes. Medical Center, 2500 N. State Street, Jackson, MS Recent findings 39216-4505, USA E-mail: rdeshazo@umc.edu Primary atrophic rhinitis usually develops as a consequence of an acute febrile illness in members of lower socioeconomic groups in developing areas of the world. The clinical Current Opinion in Allergy and Clinical Immunology 2011, 11:1–7 setting and presence of culturable Klebsialla ozenae in the purulent, foul-smelling, nasal discharge of these patients forms the basis for diagnosis. An animal model for the disease exists in swine in which case an effective vaccine has been developed. Secondary atrophic rhinosinusitis is a condition that follows destruction of the nasal mucosa by any of a number

Journal

Current Opinion in Allergy and Clinical Immunology – Wolters Kluwer Health

Published: Feb 1, 2011

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