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Advances in Cardiovascular Imaging Atrial Fibrillation Pathophysiology and Prognosis Insights From Cardiovascular Imaging Konstantinos C. Siontis, MD; Jeffrey B. Geske, MD; Bernard J. Gersh, MB, ChB, DPhil trial fibrillation (AF) is the most common sustained central focus of imaging assessment, although the importance Aarrhythmia and is characterized by ineffective atrial con- of characterizing non-LA cardiac structures through multimo- tractions and often rapid ventricular response rates. It has been dality imaging is being increasingly recognized. Herein, imag- recognized that the risk of AF increases with age and the rise ing assessment of both LA and non-LA structures is reviewed. in AF incidence in recent decades is at least partly accounted for by the aging population in addition to the increase in other Imaging the LA 1,2 risk factors, including obesity. The global estimated preva- LA Size and Shape lence of AF was >33 million in 2010, and projections indicate LA remodeling is critical in the pathogenesis and perpetuation that its incidence and prevalence could potentially increase 13 14 4 of AF. Kalifa et al demonstrated that increased LA stretch >2.5-fold by 2030. Although aging, hypertension, body mass constitutes a substrate for development of AF via the increase index, structural heart
Circulation: Cardiovascular Imaging – Wolters Kluwer Health
Published: Jun 1, 2015
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