Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Association Between Diffuse Myocardial Fibrosis by Cardiac Magnetic Resonance Contrast-Enhanced T 1 A Pilot Study

Association Between Diffuse Myocardial Fibrosis by Cardiac Magnetic Resonance Contrast-Enhanced T... Association Between Diffuse Myocardial Fibrosis by Cardiac Mapping and Magnetic Resonance Contrast-Enhanced T Subclinical Myocardial Dysfunction in Diabetic Patients A Pilot Study Arnold C.T. Ng, MBBS, PhD*; Dominique Auger, MD*; Victoria Delgado, MD, PhD; Saskia G.C. van Elderen, MD; Matteo Bertini, MD, PhD; Hans-Marc Siebelink, MD, PhD; Rob J. van der Geest, PhD; Cosimo Bonetti, PhD; Enno T. van der Velde, PhD; Albert de Roos, MD, PhD; Johannes W.A. Smit, MD, PhD; Dominic Y. Leung, MBBS, PhD; Jeroen J. Bax, MD, PhD; Hildo J. Lamb, MD, MSc, PhD Background—Diabetic patients have increased interstitial myocardial fibrosis on histological examination. Magnetic resonance imaging (MRI) T mapping is a previously validated imaging technique that can quantify the burden of global and regional interstitial fibrosis. However, the association between MRI T mapping and subtle left ventricular (LV) dysfunction in diabetic patients is unknown. Methods and Results—Fifty diabetic patients with normal LV ejection fraction (EF) and no underlying coronary artery disease or regional macroscopic scar on MRI delayed enhancement were prospectively recruited. Diabetic patients were compared with 19 healthy controls who were frequency matched in age, sex and body mass index. There were no significant differences in mean LV end-diastolic volume index, end-systolic volume http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Cardiovascular Imaging Wolters Kluwer Health

Association Between Diffuse Myocardial Fibrosis by Cardiac Magnetic Resonance Contrast-Enhanced T 1 A Pilot Study

Lamb, Hildo J.
Circulation: Cardiovascular Imaging , Volume 5 (1) – Jan 1, 2012
Download PDF
9 pages

Loading next page...
 
/lp/wolters-kluwer-health/association-between-diffuse-myocardial-fibrosis-by-cardiac-magnetic-sLgj0Zbctn

References (36)

Copyright
© 2012 American Heart Association, Inc.
ISSN
1941-9651
eISSN
1942-0080
DOI
10.1161/CIRCIMAGING.111.965608
pmid
22135399
Publisher site
See Article on Publisher Site

Abstract

Association Between Diffuse Myocardial Fibrosis by Cardiac Mapping and Magnetic Resonance Contrast-Enhanced T Subclinical Myocardial Dysfunction in Diabetic Patients A Pilot Study Arnold C.T. Ng, MBBS, PhD*; Dominique Auger, MD*; Victoria Delgado, MD, PhD; Saskia G.C. van Elderen, MD; Matteo Bertini, MD, PhD; Hans-Marc Siebelink, MD, PhD; Rob J. van der Geest, PhD; Cosimo Bonetti, PhD; Enno T. van der Velde, PhD; Albert de Roos, MD, PhD; Johannes W.A. Smit, MD, PhD; Dominic Y. Leung, MBBS, PhD; Jeroen J. Bax, MD, PhD; Hildo J. Lamb, MD, MSc, PhD Background—Diabetic patients have increased interstitial myocardial fibrosis on histological examination. Magnetic resonance imaging (MRI) T mapping is a previously validated imaging technique that can quantify the burden of global and regional interstitial fibrosis. However, the association between MRI T mapping and subtle left ventricular (LV) dysfunction in diabetic patients is unknown. Methods and Results—Fifty diabetic patients with normal LV ejection fraction (EF) and no underlying coronary artery disease or regional macroscopic scar on MRI delayed enhancement were prospectively recruited. Diabetic patients were compared with 19 healthy controls who were frequency matched in age, sex and body mass index. There were no significant differences in mean LV end-diastolic volume index, end-systolic volume

Journal

Circulation: Cardiovascular Imaging – Wolters Kluwer Health

Published: Jan 1, 2012

There are no references for this article.