Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Anti- Treponema Antibody Also Stains Helicobacter heilmannii

Anti- Treponema Antibody Also Stains Helicobacter heilmannii To the Editor: Years ago, one of us (A.F-.F.) described some crossed immunoreactions when using the antibody against Treponema in immunohistochemistry. 1 Among the bacteria that can be stained with this antibody, we reported examples of the spiral Helicobacter pylori in gastric biopsies, as well as examples of acid alcohol resistant bacilli in lung and skin biopsies. Some years later, we also reported a nonspecific immunostaining by of nonspiral bacteria found in water. 2 The purpose of this letter is to bring to your attention an additional crossed reaction that we have detected in a bacteria that is occasionally found in gastric biopsies: Helicobacter heilmannii. H. heilmannii is not as common as H. pylori : Okiyama et al 3 found H. heilmannii in only 0.1% of their endoscopic biopsies, whereas H. pylori is found in 70% of the gastric biopsies performed on symptomatic patients. 4 Like H. pylori , H. heilmannii is also a spiral microorganism, but H. heilmannii is longer than H. pylori (2.3 to 10 μm) with 4 to 6 helical turns, which gives it a corkscrew-like appearance 5,6 ( Fig. 1A ). FIGURE 1 Helicobacter heilmannii in a gastric biopsy, stained with Giemsa (A) and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Immunohistochemistry & Molecular Morphology Wolters Kluwer Health

Anti- Treponema Antibody Also Stains Helicobacter heilmannii

Loading next page...
 
/lp/wolters-kluwer-health/anti-treponema-antibody-also-stains-helicobacter-heilmannii-q90ZpHvuJq
Copyright
Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.
Subject
Online Articles: Letters to the Editor
ISSN
1541-2016
eISSN
1533-4058
DOI
10.1097/PAI.0000000000000266
pmid
26509908
Publisher site
See Article on Publisher Site

Abstract

To the Editor: Years ago, one of us (A.F-.F.) described some crossed immunoreactions when using the antibody against Treponema in immunohistochemistry. 1 Among the bacteria that can be stained with this antibody, we reported examples of the spiral Helicobacter pylori in gastric biopsies, as well as examples of acid alcohol resistant bacilli in lung and skin biopsies. Some years later, we also reported a nonspecific immunostaining by of nonspiral bacteria found in water. 2 The purpose of this letter is to bring to your attention an additional crossed reaction that we have detected in a bacteria that is occasionally found in gastric biopsies: Helicobacter heilmannii. H. heilmannii is not as common as H. pylori : Okiyama et al 3 found H. heilmannii in only 0.1% of their endoscopic biopsies, whereas H. pylori is found in 70% of the gastric biopsies performed on symptomatic patients. 4 Like H. pylori , H. heilmannii is also a spiral microorganism, but H. heilmannii is longer than H. pylori (2.3 to 10 μm) with 4 to 6 helical turns, which gives it a corkscrew-like appearance 5,6 ( Fig. 1A ). FIGURE 1 Helicobacter heilmannii in a gastric biopsy, stained with Giemsa (A) and

Journal

Applied Immunohistochemistry & Molecular MorphologyWolters Kluwer Health

Published: Mar 1, 2016

There are no references for this article.