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Anaphylaxis

Anaphylaxis EDITORIAL Educational Programs Are Needed Johannes Ring naphylaxis is the number one emergency situation in allergy. More than 100 years Aafter its first description, there are still many problems and open questions regarding pathophysiology, diagnosis, treatment, and prevention. Many national and international societies have edited guidelines that give clear recommendations for acute treatment, showing algorithms depending on the severity of the clinical symptomatology, which can be graded rather simply. Adrenaline has been shown to be the most important drug to be applied, and the intramuscular route has a clear-cut advantage over other ways of administration in the initial phase. Recently, the World Allergy Organization has published a position statement on epinephrine application as a World Allergy Organization Report. Although things seem pretty clear at a superficial glance, there are some controver- sies in detail with regard to when in the very early stage of anaphylaxis adrenaline should be given. There seems to be a divergence between pediatric allergists and allergists deal- ing more and mostly with adult patients because adrenaline has well-known pharmaco- logical effects that can be detrimental to people with severe cardiac disease, especially arrhythmia. Furthermore, problems arise in prophylactic use, which means giving anti- anaphylactic treatment http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png World Allergy Organization Journal Wolters Kluwer Health

Anaphylaxis

Ring, Johannes
World Allergy Organization Journal , Volume 1 (10) – Oct 1, 2008
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References (7)

ISSN
1939-4551
DOI
10.1097/WOX.0b013e3181897d12
pmid
23282673
Publisher site
See Article on Publisher Site

Abstract

EDITORIAL Educational Programs Are Needed Johannes Ring naphylaxis is the number one emergency situation in allergy. More than 100 years Aafter its first description, there are still many problems and open questions regarding pathophysiology, diagnosis, treatment, and prevention. Many national and international societies have edited guidelines that give clear recommendations for acute treatment, showing algorithms depending on the severity of the clinical symptomatology, which can be graded rather simply. Adrenaline has been shown to be the most important drug to be applied, and the intramuscular route has a clear-cut advantage over other ways of administration in the initial phase. Recently, the World Allergy Organization has published a position statement on epinephrine application as a World Allergy Organization Report. Although things seem pretty clear at a superficial glance, there are some controver- sies in detail with regard to when in the very early stage of anaphylaxis adrenaline should be given. There seems to be a divergence between pediatric allergists and allergists deal- ing more and mostly with adult patients because adrenaline has well-known pharmaco- logical effects that can be detrimental to people with severe cardiac disease, especially arrhythmia. Furthermore, problems arise in prophylactic use, which means giving anti- anaphylactic treatment

Journal

World Allergy Organization Journal – Wolters Kluwer Health

Published: Oct 1, 2008

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