Access the full text.
Sign up today, get DeepDyve free for 14 days.
References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.
ORIGINAL ARTICLE Analysis of Major Known Driver Mutations and Prognosis in Resected Adenosquamous Lung Carcinomas Rui Wang, MD,*† Yunjian Pan, MD,*† Chenguang Li, MD,PhD,*† Huibiao Zhang, MD,‡ David Garfield, MD,§ Yuan Li, MD, †║ Ting Ye, MD,*† Haichuan Hu, MD,*† Xiaoyang Luo, MD,*† Hang Li, MD,*† Yang Zhang, MD,*† Jie Zhang, MD,*† Xiaoyan Zhou, MD,†║ Lei Shen, MD,†║ William Pao, MD,PhD,¶ Yihua Sun, MD,*† and Haiquan Chen, MD*† ung cancer is the most common cause of cancer-related death Introduction: Genotyping for driver mutations is now routinely used Lworldwide. Adenosquamous lung carcinoma (AdSqLC) is to guide clinical care of patients with lung cancer. Adenosquamous a subtype of non–small-cell lung cancer (NSCLC), account- lung carcinoma (AdSqLC) is a subtype of cancer that contains both 2–4 ing for 1.6% to 4.5% of lung cancers. According to World adenocarcinoma and squamous cell carcinoma. However, the inci- Health Organization classification, AdSqLC is defined as a dence, clinicopathologic characteristics, and prognostic implications carcinoma showing components of both adenocarcinoma and of major driver mutations in AdSqLCs are not well established. squamous cell carcinoma, with each component comprising Methods: Seventy-six resected AdSqLCs and 646 lung adenocarci- at least 10% of the tumor. AdSqLCs have more aggressive nomas were screened for known genetic alterations involving EGFR, behavior and worse
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Jun 1, 2014
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.