Access the full text.
Sign up today, get DeepDyve free for 14 days.
V. Muthurangu, D. Atkinson, Maxime Sermesant, M. Miquel, S. Hegde, Robert Johnson, R. Andriantsimiavona, A. Taylor, E. Baker, R. Tulloh, D. Hill, R. Razavi (2005)
Measurement of total pulmonary arterial compliance using invasive pressure monitoring and MR flow quantification during MR-guided cardiac catheterization.American journal of physiology. Heart and circulatory physiology, 289 3
J. Chirinos, J. Kips, D. Jacobs, L. Brumback, D. Duprez, R. Kronmal, D. Bluemke, R. Townsend, S. Vermeersch, P. Segers (2012)
Arterial wave reflections and incident cardiovascular events and heart failure: MESA (Multiethnic Study of Atherosclerosis).Journal of the American College of Cardiology, 60 21
Michal Schäfer, D. Ivy, S. Abman, Alex Barker, Lorna Browne, Brian Fonseca, V. Kheyfets, Kendall Hunter, U. Truong (2017)
Apparent Aortic Stiffness in Children With Pulmonary Arterial Hypertension: Existence of Vascular Interdependency?Circulation: Cardiovascular Imaging, 10
A. Noordegraaf, B. Westerhof, N. Westerhof (2017)
The Relationship Between the Right Ventricle and its Load in Pulmonary Hypertension.Journal of the American College of Cardiology, 69 2
B. Pandya, M. Quail, J. Steeden, A. McKee, F. Odille, A. Taylor, I. Schulze-Neick, G. Derrick, S. Moledina, V. Muthurangu (2014)
Real-Time Magnetic Resonance Assessment of Septal Curvature Accurately Tracks Acute Hemodynamic Changes in Pediatric Pulmonary HypertensionCirculation: Cardiovascular Imaging, 7
W. Nichols, C. Vlachopoulos (1998)
McDonald's Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles
Shigeki Kobayashi, M. Yano, M. Kohno, M. Obayashi, Yuji Hisamatsu, T. Ryoke, T. Ohkusa, K. Yamakawa, Masunori Matsuzaki (1996)
Influence of aortic impedance on the development of pressure-overload left ventricular hypertrophy in rats.Circulation, 94 12
M. Quail, D. Knight, J. Steeden, L. Taelman, S. Moledina, A. Taylor, P. Segers, G. Coghlan, V. Muthurangu (2015)
Noninvasive pulmonary artery wave intensity analysis in pulmonary hypertensionAmerican Journal of Physiology - Heart and Circulatory Physiology, 308
Daniel Knight, J. Steeden, S. Moledina, Alexander Jones, J. Coghlan, V. Muthurangu (2015)
Left ventricular diastolic dysfunction in pulmonary hypertension predicts functional capacity and clinical worsening: a tissue phase mapping studyJournal of Cardiovascular Magnetic Resonance, 17
K. Parker, C. Jones (1990)
Forward and backward running waves in the arteries: analysis using the method of characteristics.Journal of biomechanical engineering, 112 3
J. Lankhaar, N. Westerhof, T. Faes, K. Marques, J. Marcus, P. Postmus, A. Vonk-Noordegraaf (2006)
Quantification of right ventricular afterload in patients with and without pulmonary hypertension.American journal of physiology. Heart and circulatory physiology, 291 4
J. Chirinos, P. Segers (2010)
Noninvasive evaluation of left ventricular afterload: part 2: arterial pressure-flow and pressure-volume relations in humans.Hypertension, 56 4
M. Veerdonk, T. Kind, J. Marcus, G. Mauritz, M. Heymans, H. Bogaard, H. Bogaard, A. Boonstra, K. Marques, N. Westerhof, A. Vonk-Noordegraaf (2011)
Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy.Journal of the American College of Cardiology, 58 24
Editorial Adverse Pulmonary–Aortic Interactions in Pulmonary Hypertension Michael A. Quail, MBChB, PhD; Vivek Muthurangu, MD ascular remodeling in pulmonary hypertension (PH) compliance. This is the characteristic impedance (Z ) of the Vcauses increased ventricular afterload, resulting in vessel, and Z governs ventricular load in early systole. The Z c c right ventricular failure and high mortality. Afterload is the is directly related to pulse wave velocity (c) as follows: mechanical impedance imposed by the arterial tree, against which the ventricle must work to eject blood. Despite the Z =ρcA /, (1) cd tendency to conflate afterload with blood pressure, it cannot where A is vessel diastolic area, and ρ is blood density. As be reduced to a single number or variable. Instead it is more 2,3 can be seen from Equation 1, ventricular load in early sys- appropriately defined in terms of pressure-flow relations. tole is increased in vessels with smaller areas and elevated See Article by Schäfer et al 10 9 pulse wave velocity. Therefore, Schäfer et al results imply Afterload is divided into several steady and pulsatile com- increased aortic Z in pediatric PH patients and increased LV ponents, including vascular resistance, total arterial compli- afterload. However,
Circulation: Cardiovascular Imaging – Wolters Kluwer Health
Published: Feb 1, 2017
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.