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An Unusual Case of Hydrogen Peroxide-Induced Injury Presenting With Gas Gangrene

An Unusual Case of Hydrogen Peroxide-Induced Injury Presenting With Gas Gangrene Downloaded from http://journals.lww.com/americantherapeutics by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/04/2020 American Journal of Therapeutics 0, 1–3 (2020) An Unusual Case of Hydrogen Peroxide-Induced Injury Presenting With Gas Gangrene To the Editor: wound at home. He noted while using it his skin felt like it was burning and when it turned dark after a few days, he discontinued it. The patient was working barefoot in INTRODUCTION his garden during this time. He was started on intravenous vancomycin and Gas gangrene or myonecrosis is an aggressive tissue infec- piperacillin–tazobactam. Given the presentation of the tion commonlycausedbyanaerobic Clostridia species. patient in sepsis, emergent surgical consultation was done. Here we present an unusual case where hydrogen perox- An emergent right mid-leg guillotine amputation was per- ide (H O )-induced injury culminated in a gas gangrene. 2 2 formed, with foul smelling acute necrotizing inflamma- tion, abscess, and bone necrosis noted in the specimen. CASE Infectious disease was consulted and intravenous antibi- otics were continued. Few days later, when the patient improved, he underwent a complete below knee amputa- A 61-year-old Caucasian gentleman with past medical tion with muscle flap reconstruction. After this procedure, history of hypertension, peripheral arterial disease and the patient steadily improved and was http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Therapeutics Wolters Kluwer Health

An Unusual Case of Hydrogen Peroxide-Induced Injury Presenting With Gas Gangrene

American Journal of Therapeutics , Volume Publish Ahead of Print – Jan 1, 2020

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Publisher
Wolters Kluwer Health
ISSN
1075-2765
eISSN
1536-3686
DOI
10.1097/MJT.0000000000001197
Publisher site
See Article on Publisher Site

Abstract

Downloaded from http://journals.lww.com/americantherapeutics by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/04/2020 American Journal of Therapeutics 0, 1–3 (2020) An Unusual Case of Hydrogen Peroxide-Induced Injury Presenting With Gas Gangrene To the Editor: wound at home. He noted while using it his skin felt like it was burning and when it turned dark after a few days, he discontinued it. The patient was working barefoot in INTRODUCTION his garden during this time. He was started on intravenous vancomycin and Gas gangrene or myonecrosis is an aggressive tissue infec- piperacillin–tazobactam. Given the presentation of the tion commonlycausedbyanaerobic Clostridia species. patient in sepsis, emergent surgical consultation was done. Here we present an unusual case where hydrogen perox- An emergent right mid-leg guillotine amputation was per- ide (H O )-induced injury culminated in a gas gangrene. 2 2 formed, with foul smelling acute necrotizing inflamma- tion, abscess, and bone necrosis noted in the specimen. CASE Infectious disease was consulted and intravenous antibi- otics were continued. Few days later, when the patient improved, he underwent a complete below knee amputa- A 61-year-old Caucasian gentleman with past medical tion with muscle flap reconstruction. After this procedure, history of hypertension, peripheral arterial disease and the patient steadily improved and was

Journal

American Journal of TherapeuticsWolters Kluwer Health

Published: Jan 1, 2020

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