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Adverse reactions to and safety of newer disease‐modifying antirheumatic drugs for rheumatoid arthritis

Adverse reactions to and safety of newer disease‐modifying antirheumatic drugs for... New agents to treat rheumatoid arthritis have transformed clinical practice, but have introduced new potential adverse reactions. The tumour necrosis factor-α inhibitors can cause a variety of hypersensitivity reactions, and increase the risk of infections including tuberculosis. They can precipitate heart failure, and may increase the risk of lymphoma, and exacerbate multiple sclerosis. The major adverse effects of leflunomide are diarrhoea and rashes and there are concerns about liver damage. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Adverse Drug Reaction Bulletin Wolters Kluwer Health

Adverse reactions to and safety of newer disease‐modifying antirheumatic drugs for rheumatoid arthritis

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Copyright
© 2003 Lippincott Williams & Wilkins
ISSN
0044-6394
eISSN
2159-7774

Abstract

New agents to treat rheumatoid arthritis have transformed clinical practice, but have introduced new potential adverse reactions. The tumour necrosis factor-α inhibitors can cause a variety of hypersensitivity reactions, and increase the risk of infections including tuberculosis. They can precipitate heart failure, and may increase the risk of lymphoma, and exacerbate multiple sclerosis. The major adverse effects of leflunomide are diarrhoea and rashes and there are concerns about liver damage.

Journal

Adverse Drug Reaction Bulletin – Wolters Kluwer Health

Published: Dec 1, 2003

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