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Additional Magnetic Resonance Imaging–Detected Suspicious Lesions in Known Patients With Breast Cancer

Additional Magnetic Resonance Imaging–Detected Suspicious Lesions in Known Patients With Breast... Purpose The aim of the study was to compare the performances of second-look digital breast tomosynthesis (DBT) and ultrasonography (US) for additional magnetic resonance imaging (MRI)–detected suspicious lesions in patients referred for breast cancer. Methods Fifty-five patients (52.5 [9.3] years) with breast cancers newly diagnosed at a referring hospital underwent MRI and afterward DBT and US in our institution. The frequency for detecting additional MRI-detected suspicious lesions on DBT and US and performances of DBT and US were compared. Results Of 37 additional MRI-detected suspicious lesions, 27 were detected on DBT and/or US; 2 were detected on both DBT and US, 1 was detected only on DBT, and 24 were detected only on US. Ultrasonography detected more additional suspicious lesions than DBT (P < 0.0001). Twelve (44.4%) of the 27 lesions were malignant. The sensitivity and negative predictive value of US (100.0% and 100.0%) were significantly higher than those of DBT (16.7% and 83.6%, P < 0.001 and P = 0.001). The specificity of DBT was significantly higher (98.1%) than that of US (78.9%, P = 0.002). Positive predictive values of DBT and US were not significantly different (66.7% vs 52.2%, P = 0.598). The area under the receiver operating characteristic curve of US was significantly higher (0.894) than that of DBT (0.574, P < 0.001). Conclusions Second-look US showed higher performances than DBT for detecting and characterizing suspicious lesions additionally detected on MRI in patients referred for breast cancer. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Ultrasound quarterly Wolters Kluwer Health

Additional Magnetic Resonance Imaging–Detected Suspicious Lesions in Known Patients With Breast Cancer

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References (31)

Publisher
Wolters Kluwer Health
Copyright
Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.
ISSN
0894-8771
eISSN
1536-0253
DOI
10.1097/RUQ.0000000000000273
pmid
28221238
Publisher site
See Article on Publisher Site

Abstract

Purpose The aim of the study was to compare the performances of second-look digital breast tomosynthesis (DBT) and ultrasonography (US) for additional magnetic resonance imaging (MRI)–detected suspicious lesions in patients referred for breast cancer. Methods Fifty-five patients (52.5 [9.3] years) with breast cancers newly diagnosed at a referring hospital underwent MRI and afterward DBT and US in our institution. The frequency for detecting additional MRI-detected suspicious lesions on DBT and US and performances of DBT and US were compared. Results Of 37 additional MRI-detected suspicious lesions, 27 were detected on DBT and/or US; 2 were detected on both DBT and US, 1 was detected only on DBT, and 24 were detected only on US. Ultrasonography detected more additional suspicious lesions than DBT (P < 0.0001). Twelve (44.4%) of the 27 lesions were malignant. The sensitivity and negative predictive value of US (100.0% and 100.0%) were significantly higher than those of DBT (16.7% and 83.6%, P < 0.001 and P = 0.001). The specificity of DBT was significantly higher (98.1%) than that of US (78.9%, P = 0.002). Positive predictive values of DBT and US were not significantly different (66.7% vs 52.2%, P = 0.598). The area under the receiver operating characteristic curve of US was significantly higher (0.894) than that of DBT (0.574, P < 0.001). Conclusions Second-look US showed higher performances than DBT for detecting and characterizing suspicious lesions additionally detected on MRI in patients referred for breast cancer.

Journal

Ultrasound quarterly – Wolters Kluwer Health

Published: Jan 1, 2017

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