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A Novel Index of Remodeling in Hypertensive Heart Disease

A Novel Index of Remodeling in Hypertensive Heart Disease Editorial Gerard P. Aurigemma, MD; Michael Salerno, MD, PhD, MS eft ventricular hypertrophy (LVH) is thought to be an concentric remodeling, a term they introduced, was defined as Ladaptive response that allows for normal ejection frac- an elevated RWT without LVH. Interestingly, in this and other tion despite abnormal pressure or volume load, or a combined studies, the majority of the hypertensive patients had neither pressure and volume load. However, this adaptation is asso- hypertrophy nor concentric geometry. ciated with substantially increased morbidity and mortality. This paradigm has arguably become the way that most Echocardiography helped create the dossier on the preva- of us think about the adaptation to pressure overload, has lence and consequences of LVH in hypertension and outcome been refined with some modifications, such as indexation for 3,4 9 response to treatment. Echocardiography and now cardiac height and other allometric measures, and made its way into 4,10 guideline documents. One might add that the interest in magnetic resonance imaging (CMR), a more precise means to measure LVH, have been used in cross-sectional and epide- the field of remodeling in pressure overload has experienced 4,5 miological studies and serially in clinical trials. a renaissance with the introduction http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Cardiovascular Imaging Wolters Kluwer Health

A Novel Index of Remodeling in Hypertensive Heart Disease

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References (24)

Publisher
Wolters Kluwer Health
Copyright
© 2017 American Heart Association, Inc.
ISSN
1941-9651
eISSN
1942-0080
DOI
10.1161/CIRCIMAGING.117.006975
Publisher site
See Article on Publisher Site

Abstract

Editorial Gerard P. Aurigemma, MD; Michael Salerno, MD, PhD, MS eft ventricular hypertrophy (LVH) is thought to be an concentric remodeling, a term they introduced, was defined as Ladaptive response that allows for normal ejection frac- an elevated RWT without LVH. Interestingly, in this and other tion despite abnormal pressure or volume load, or a combined studies, the majority of the hypertensive patients had neither pressure and volume load. However, this adaptation is asso- hypertrophy nor concentric geometry. ciated with substantially increased morbidity and mortality. This paradigm has arguably become the way that most Echocardiography helped create the dossier on the preva- of us think about the adaptation to pressure overload, has lence and consequences of LVH in hypertension and outcome been refined with some modifications, such as indexation for 3,4 9 response to treatment. Echocardiography and now cardiac height and other allometric measures, and made its way into 4,10 guideline documents. One might add that the interest in magnetic resonance imaging (CMR), a more precise means to measure LVH, have been used in cross-sectional and epide- the field of remodeling in pressure overload has experienced 4,5 miological studies and serially in clinical trials. a renaissance with the introduction

Journal

Circulation: Cardiovascular ImagingWolters Kluwer Health

Published: Sep 1, 2017

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