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Xenotransplant News

Xenotransplant News European surgeons transplant windpipe created from stem cells* In a feat of biomedical engineering, doctors have given a woman a new windpipe with tissue grown from her own stem cells, eliminating the need for anti‐rejection drugs. If successful, the procedure could become a new standard of treatment, the Associated Press reports. The results were published in The Lancet (Nov 18 2008; Epub. ahead of print). The transplant was given to a 30‐yr‐old mother of two living in Barcelona, Spain who has suffered from tuberculosis for years. After a severe collapse of her left lung she needed regular hospital visits to clear her airways and was unable to take care of her children. Doctors initially thought the only solution was to remove the entire left lung. But Dr. P. Macchiarini, head of thoracic surgery at Barcelona’s Hospital Clinic, proposed a windpipe transplant instead. Once doctors had a donor windpipe, scientists at Italy’s University of Padua stripped off all its cells, leaving only a tube of connective tissue. Meanwhile, doctors at the University of Bristol, UK used the patients bone marrow’s stem cells to create millions of cartilage and tissue cells to cover and line the windpipe. Experts at the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Xenotransplantation Wiley

Xenotransplant News

Xenotransplantation , Volume 16 (1) – Jan 1, 2009

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Publisher
Wiley
Copyright
© 2009 John Wiley & Sons A/S
ISSN
0908-665X
eISSN
1399-3089
DOI
10.1111/j.1399-3089.2008.00506.x
Publisher site
See Article on Publisher Site

Abstract

European surgeons transplant windpipe created from stem cells* In a feat of biomedical engineering, doctors have given a woman a new windpipe with tissue grown from her own stem cells, eliminating the need for anti‐rejection drugs. If successful, the procedure could become a new standard of treatment, the Associated Press reports. The results were published in The Lancet (Nov 18 2008; Epub. ahead of print). The transplant was given to a 30‐yr‐old mother of two living in Barcelona, Spain who has suffered from tuberculosis for years. After a severe collapse of her left lung she needed regular hospital visits to clear her airways and was unable to take care of her children. Doctors initially thought the only solution was to remove the entire left lung. But Dr. P. Macchiarini, head of thoracic surgery at Barcelona’s Hospital Clinic, proposed a windpipe transplant instead. Once doctors had a donor windpipe, scientists at Italy’s University of Padua stripped off all its cells, leaving only a tube of connective tissue. Meanwhile, doctors at the University of Bristol, UK used the patients bone marrow’s stem cells to create millions of cartilage and tissue cells to cover and line the windpipe. Experts at the

Journal

XenotransplantationWiley

Published: Jan 1, 2009

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