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M. Seyfarth, D. Sibbing, I. Bauer, G. Fröhlich, Lorenz Bott-Flügel, R. Byrne, J. Dirschinger, A. Kastrati, A. Schömig (2008)
A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock caused by myocardial infarction.Journal of the American College of Cardiology, 52 19
Antoniucci (2003)
Does gender affect the clinical outcome of patients with acute myocardial infarction complicated by cardiogenic shock who undergo percutaneous coronary interventionCatheter Cardiovasc Interv, 59
J. Dickerson, H. Nagaraja, S. Raman (2010)
Gender‐Related Differences in Coronary Artery Dimensions: A Volumetric AnalysisClinical Cardiology, 33
J. Hochman, L. Sleeper, E. Godfrey, S. Mckinlay, T. Sanborn, J. Col, T. LeJemtel (1999)
SHould we emergently revascularize Occluded Coronaries for cardiogenic shocK: an international randomized trial of emergency PTCA/CABG-trial design. The SHOCK Trial Study Group.American heart journal, 137 2
D. Campbell, J. Somaratne, A. Jenkins, D. Prior, M. Yii, J. Kenny, A. Newcomb, D. Kelly, M. Black (2011)
Differences in Myocardial Structure and Coronary Microvasculature Between Men and Women With Coronary Artery DiseaseHypertension, 57
U. Zeymer, A. Vogt, R. Zahn, Michael Weber, U. Tebbe, M. Gottwik, T. Bonzel, J. Senges, K. Neuhaus (2004)
Predictors of in-hospital mortality in 1333 patients with acute myocardial infarction complicated by cardiogenic shock treated with primary percutaneous coronary intervention (PCI); Results of the primary PCI registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK).European heart journal, 25 4
R. Glaser, H. Herrmann, S. Murphy, L. Demopoulos, Peter Dibattiste, C. Cannon, E. Braunwald (2002)
Benefit of an early invasive management strategy in women with acute coronary syndromes.JAMA, 288 24
A. Go, D. Mozaffarian, V. Roger, E. Benjamin, J. Berry, M. Blaha, S. Dai, E. Ford, C. Fox, Sheila Franco, H. Fullerton, C. Gillespie, S. Hailpern, J. Heit, V. Howard, Mark Huffman, S. Judd, B. Kissela, S. Kittner, D. Lackland, J. Lichtman, L. Lisabeth, R. Mackey, D. Magid, G. Marcus, A. Marelli, D. Matchar, Darren Mcguire, E. Mohler, C. Moy, M. Mussolino, R. Neumar, G. Nichol, D. Pandey, N. Paynter, M. Reeves, P. Sorlie, J. Stein, A. Towfighi, T. Turan, S. Virani, N. Wong, D. Woo, M. Turner (2014)
Heart disease and stroke statistics--2014 update: a report from the American Heart Association.Circulation, 129 3
William O'Neill, T. Schreiber, D. Wohns, C. Rihal, Srihari Naidu, ANDREW Civitello, Simon Dixon, JOSEPH Massaro, Brijeshwar Maini, E. Ohman (2013)
The Current Use of Impella 2.5 in Acute Myocardial Infarction Complicated by Cardiogenic Shock: Results from the USpella RegistryJournal of Interventional Cardiology, 27
Monique Anderson, E. Peterson, S. Peng, Tracy Wang, E. Ohman, Deepak Bhatt, J. Saucedo, M. Roe (2013)
Differences in the Profile, Treatment, and Prognosis of Patients With Cardiogenic Shock by Myocardial Infarction Classification: A Report From NCDRCirculation: Cardiovascular Quality and Outcomes, 6
S. Dhruva, L. Bero, R. Redberg (2011)
Gender Bias in Studies for Food and Drug Administration Premarket Approval of Cardiovascular DevicesCirculation: Cardiovascular Quality and Outcomes, 4
A. Blomkalns, A. Chen, J. Hochman, E. Peterson, Kelly Trynosky, D. Diercks, G. Brogan, W. Boden, M. Roe, E. Ohman, W. Gibler, L. Newby (2005)
Gender disparities in the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes: large-scale observations from the CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation of the American College of Cardiology/AmeriJournal of the American College of Cardiology, 45 6
S. Sheifer, M. Canos, K. Weinfurt, U. Arora, F. Mendelsohn, B. Gersh, N. Weissman (2000)
Sex differences in coronary artery size assessed by intravascular ultrasound.American heart journal, 139 4
Kerry Lee, L. Woodlief, E. Topol, W. Weaver, A. Betriu, J. Col, M. Simoons, P. Aylward, F. Werf, R. Califf (1995)
Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I Investigators.Circulation, 91 6
K. Fengler, G. Fuernau, S. Desch, I. Eitel, F. Neumann, H. Olbrich, Antoinette Waha, S. Waha, G. Richardt, M. Hennersdorf, K. Empen, R. Hambrecht, J. Fuhrmann, M. Böhm, J. Poess, R. Strasser, S. Schneider, G. Schuler, K. Werdan, U. Zeymer, H. Thiele (2014)
Gender differences in patients with cardiogenic shock complicating myocardial infarction: a substudy of the IABP-SHOCK II-trialClinical Research in Cardiology, 104
Nausheen Akhter, Sarah Milford-Beland, M. Roe, R. Piana, J. Kao, A. Shroff (2009)
Gender differences among patients with acute coronary syndromes undergoing percutaneous coronary intervention in the American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR).American heart journal, 157 1
R. Fincke, J. Hochman, A. Lowe, V. Menon, J. Slater, J. Webb, T. LeJemtel, G. Cotter (2004)
Cardiac power is the strongest hemodynamic correlate of mortality in cardiogenic shock: a report from the SHOCK trial registry.Journal of the American College of Cardiology, 44 2
S. Gharacholou, K. Alexander, A. Chen, Tracy Wang, C. Melloni, W. Gibler, C. Pollack, E. Ohman, E. Peterson, M. Roe (2010)
Implications and reasons for the lack of use of reperfusion therapy in patients with ST-segment elevation myocardial infarction: findings from the CRUSADE initiative.American heart journal, 159 5
D. Morrow, E. Antman, A. Charlesworth, Richard Cairns, S. Murphy, J. Lemos, R. Giugliano, C. Mccabe, E. Braunwald (2000)
TIMI Risk Score for ST-Elevation Myocardial Infarction: A Convenient, Bedside, Clinical Score for Risk Assessment at Presentation: An Intravenous nPA for Treatment of Infarcting Myocardium Early II Trial SubstudyCirculation: Journal of the American Heart Association, 102
S. Normand, M. Glickman, R. Sharma, B. Mcneil (1996)
Using admission characteristics to predict short-term mortality from myocardial infarction in elderly patients. Results from the Cooperative Cardiovascular Project.JAMA, 275 17
S. Wong, L. Sleeper, E. Monrad, M. Menegus, A. Palazzo, V. Džavík, A. Jacobs, Xianjiao Jiang, J. Hochman (2001)
Absence of gender differences in clinical outcomes in patients with cardiogenic shock complicating acute myocardial infarction. A report from the SHOCK Trial Registry.Journal of the American College of Cardiology, 38 5
Objectives The aim of this analysis was to assess survival differences between men and women supported with Impella 2.5 (Abiomed Inc., Danvers) in the setting of acute myocardial infarction (AMI) complicated by cardiogenic shock (CS). Background Data on sex differences in outcomes of CS with mechanical circulatory support are sparse. Methods Patients enrolled in the cVAD Registry who underwent percutaneous coronary intervention (PCI) and Impella 2.5 support for CS complicating an AMI were included. Differences between men and women were examined. Results In total, 180 patients were analyzed. Women (n = 49, 27.2%) were older (71.0 ± 12.8 years vs 63.8 ± 13.0, P = 0.001), smaller (BSA 1.82 ± 0.22 vs 2.04 ± 0.24 m2, P < 0.001), and had a higher STS mortality risk score than men (27.9 ± 17.0 vs. 20.8 ± 16.8 P = 0.01). There was no difference in survival to discharge (P = 0.3). Patients receiving the Impella 2.5 pre‐PCI had significantly lower inpatient mortality than those who received support post‐PCI (P = 0.003). However, the magnitude of the survival benefit was significantly greater in women who received the Impella pre‐PCI as compared to men. Overall, 68.8% of women survived with pre‐PCI Impella 2.5 versus 24.2% post‐PCI (P = 0.005) whereas 54.2% of men survived with pre‐PCI Impella 2.5 versus 40.3% post‐PCI (P = 0.1, p‐interaction = 0.07). No differences in timing to intervention were found between men and women. Conclusions Early initiation of hemodynamic support prior to PCI with Impella 2.5, in the setting of AMI complicated by CS, was associated with a greater survival benefit to hospital discharge in women compared to men, despite a higher predicted risk of mortality and a greater revascularization failure rate for women. (J Interven Cardiol 2016;29:248–256)
Journal of Interventional Cardiology – Wiley
Published: Jun 1, 2016
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