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Ann. Hum. Genet. (1997), 61, 173±180 173 Printed in Great Britain Reviews by Muller in 1928 as the start of the ®eld when he Environmental Mutagenesis. Edited by D. H. demonstrated that X-rays could induce heritable Phillips and S. Venitt, Bios Scienti®c gene mutations in Drosophila melanogaster.In Publishers, Oxford, U.K., 1995, Pp. 403. the ensuing period it was shown that also The book comprises 18 Chapters written by chemicals were capable of inducing mutations. authors with the greatest expertise in their ®elds. The ®rst example was mustard gas, a bi- It is a timely new compilation of the correlation functional alkylating agent, extensively used in between exposure to environmental agents and World War I and even during the war between an increase in the burden of mutations in the Iran and Iraq. The similarity of effects to ionising populations of organisms which receive that radiation created the term of ` radiomimetic ' exposure. The book gives background infor- chemicals for bifunctional nitrogen mustards mation on the relationship between mutagenicity which subsequently were discovered to be useful testing, germ line mutagenesis and cancer, and as anticancer drugs. The personal environment describes and discusses methods in mutation changed with the adoption
Annals of Human Genetics – Wiley
Published: Jan 1, 1997
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