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A. Arnold, P. Serruys, W. Rutsch, M. Simoons, D. Bono, J. Tijssen, J. Lubsen, M. Verstraete (1991)
Reasons for the lack of benefit of immediate angioplasty during recombinant tissue plasminogen activator therapy for acute myocardial infarction: a regional wall motion analysis. European Cooperative Study Group.Journal of the American College of Cardiology, 17 1
J. Willems, R. Willems, I. Bijnens, R. Doerr, M. Verstraete (1991)
Value of electrocardiographic scoring systems for the assessment of thrombolytic therapy in acute myocardial infarction. The European Cooperative Study Group for Recombinant Tissue Type Plasminogen Activator.European heart journal, 12 3
N Engl J Med, 301
A. Arnold, M. Simoons, F. Werf, D. Bono, J. Lubsen, J. Tijssen, P. Serruys, M. Verstraete (1992)
Recombinant Tissue‐Type Plasminogen Activator and Immediate Angioplasty in Acute Myocardial Infarction: One‐Year Follow‐upCirculation, 86
T. Lenderink, M. Simoons, G. Es, F. Werf, M. Verstraete, A. Arnold (1995)
Benefit of thrombolytic therapy is sustained throughout five years and is related to TIMI perfusion grade 3 but not grade 2 flow at discharge. The European Cooperative Study Group.Circulation, 92 5
Roberts Roberts, Buja Buja (1972)
The frequency and significance of coronary arterial thrombi and other observations after acute myocardial infarctionAm J Med, 52
Willems Willems, Willems Willems, Bijnens Bijnens (1991)
Value of electrocar‐diographic scoring systems for the assessment of thrombolytic therapy in acute myocardial infarctionEur Heart J, 12
P. Serruys, A. Arnold, Ronald Brower, D. Bono, M. Bokslag, J. Lubsen, Johan Reiber, W. Rutsch, R. Uebis, Alec Vahanian, M. Verstraete (1987)
Effect of continued rt-PA administration on the residual stenosis after initially successful recanalization in acute myocardial infarction--a quantitative coronary angiography study of a randomized trial.European heart journal, 8 11
Simoons Simoons, Arnold Arnold, Betriu Betriu (1988)
Thrombolysis with rt‐PA in acute myocardial infarction: No additional benefit of immediate PTCALancet, 1
Rapold Rapold, Bono Bono, Arnold Arnold (1992)
for the European Cooperative Study Group. Plasma fibrinopeptide A levels in patients with acute myocardial infarction treated with alteplase: Correlation with concomitant heparin, coronary artery patency, and recurrent ischemiaCirculation, 85
L. Mortelmans, J. Vanhaecke, E. Lesaffre, A. Arnold, J. Urbain, W. Hermens, M. Roo, H. Geest, M. Verstraete, F. Werf (1990)
Evaluation of the effect of thrombolytic treatment on infarct size and left ventricular function by enzymatic, scintigraphic, and angiographic methods. The European Cooperative Study Group for Recombinant Tissue Type Plasminogen Activator.American heart journal, 119 6
H. Gold, R. Leinbach, H. Garabedian, Tsunehiro Yasuda, Jennifer Johns, ELLIOrT Grossbard, Igor Palacios, DEISIRE'COLLEN (1986)
Acute coronary reocclusion after thrombolysis with recombinant human tissue-type plasminogen activator: prevention by a maintenance infusion.Circulation, 73 2
H. Rapold, D. Bono, A. Arnold, J. Arnout, F. Cock, D. Collen, M. Verstraete (1992)
Plasma Fibrinopeptide A Levels in Patients With Acute Myocardial Infarction Treated With Alteplase: Correlation With Concomitant Heparin, Coronary Artery Patency, and Recurrent IschemiaCirculation, 85
A. Amery, G. Roeber, H. Vermeulen, M. Verstraete (1969)
Single-blind randomised multicentre trial comparing heparin and streptokinase treatment in recent myocardial infarction.Acta medica Scandinavica. Supplementum, 505
W. Roberts, L. Buja (1972)
The frequency and significance of coronary arterial thrombi and other observations in fatal acute myocardial infarction: a study of 107 necropsy patients.The American journal of medicine, 52 4
Amery Amery, Roeber Roeber, Vermeulen Vermeulen (1969)
Single‐blind randomised multicentre trial of comparing heparin and strcptokinase in recent myocardial infarctionActa Med Scand, 505
Serruys Serruys, Arnold Arnold, Brower Brower (1987)
for the European Cooperative Study Group for rt‐PA. Effect of continued rt‐PA administration on the residual stenosis after initial successful recanalization in acute myocardial infarction—a quantitative coronary angiography study of a randomized trialEur Heart J, 8
J. Willems, R. Willems, G. Willems, A. Arnold, F. Werf, M. Verstraete (1990)
Significance of initial ST segment elevation and depression for the management of thrombolytic therapy in acute myocardial infarction. European Cooperative Study Group for Recombinant Tissue-Type Plasminogen Activator.Circulation, 82 4
D. Bono, M. Simoons, J. Tijssen, A. Arnold, A. Betriu, C. Burgersdijk, L. Bescós, E. Mueller, M. Pfisterer, F. Werf (1992)
Effect of early intravenous heparin on coronary patency, infarct size, and bleeding complications after alteplase thrombolysis: results of a randomised double blind European Cooperative Study Group trial.British Heart Journal, 67
Arnold Arnold, Serruys Serruys, Rutsch Rutsch (1991)
for the European Cooperative Study Group for rt‐PA. Reasons for no additional benefit of angioplasty immediately after recombinant tissue plasminogen activator for acute myocardial infarction: A regional wall motion analysisJACC, 17
A. Arnold, D. Bono, J. Lubsen, M. Simoons, F. Werf, M. Verstraete (1994)
The Clinical Trials of the European Cooperative Study for Recombinant Tissue-Type Plasminogen Activator (rt-PA)
Mortelmans Mortelmans, Scheys Scheys, Brzostek Brzostek (1993)
Early and late effects of rt‐PA vs placebo on left ventricular function measured by nuclear ventriculographyNucl Med, 32
M. Verstraete, A. Arnold, Ronald Brower, D. Collen, D. Bono, C. Zwaan, Rainer Erbel, W. Hillis, R.John Lennane, J. Lubsen, D. Mathey, Douglas Reid, W. Rutsch, Michael Schartl, Joachim Schofer, P. Serruys, M. Simoons, R. Uebis, Alec Vahanian, F. Verheugt, Rainer Essen (1987)
Acute coronary thrombolysis with recombinant human tissue-type plasminogen activator: initial patency and influence of maintained infusion on reocclusion rate.The American journal of cardiology, 60 4
Loo Loo (1963)
Möglichkeiten und grenzen der kombinierten fibrinolyse‐antikoagulantien‐therapie des myokardinfarktesMed Klin, 58
M. Verstraete, R. Brower, D. Collen, A. Dunning, J. Lubsen, P. Michel, J. Schofer, J. Vanhaecke, F. Werf, W. Bleifeld, B. Charbonnier, D. Bono, R. Lennane, D. Mathey, P. Raynaud, A. Vahanian, G.A.vande Kley, R. Essen (1985)
DOUBLE-BLIND RANDOMISED TRIAL OF INTRAVENOUS TISSUE-TYPE PLASMINOGEN ACTIVATOR VERSUS PLACEBO IN ACUTE MYOCARDIAL INFARCTIONThe Lancet, 326
Mortelmans Mortelmans, Vanhaecke Vanhaecke, Lesaffre Lesaffre (1990)
Evaluation of the effect of thrombolytic treatment on infarct size and left ventricular function by enzymatic, scintigraphic, and angio‐graphic methodsAm Heart J, 119
Lenderink Lenderink, Simoons Simoons, Es Es (1995)
Benefit of thrombolytic therapy is sustained throughout five years and is related to TIMI perfusion garde 3 but not grade 2 flow at dischargeCirculation, 92
P. Serruys, A. Boer (1987)
Angina pectoris. What will be the requirements for acute interventional procedures in Europe?European heart journal, 8 Suppl F
M. Verstraete, M. Bory, D. Collen, R. Erbel, R. Lennane, D. Mathey, H. Michels, M. Schartl, R. Uebis, R. Bernard, R. Brower, D. Bono, W. Huhmann, J. Lubsen, J. Meyer, W. Rutsch, W. Schmidt, R. Essen (1985)
RANDOMISED TRIAL OF INTRAVENOUS RECOMBINANT TISSUE-TYPE PLASMINOGEN ACTIVATOR VERSUS INTRAVENOUS STREPTOKINASE IN ACUTE MYOCARDIAL INFARCTION Report from the European Cooperative Study Group for Recombinant Tissue-type Plasminogen ActivatorThe Lancet, 325
Verstraete Verstraete, Bernard Bernard, Bory Bory (1985)
Randomised trial of intravenous recombinant tissue‐type plasminogen activator versus intravenous Streptokinase in acute myocardial infarctionLancet, 1
Verstraete Verstraete, Arnold Arnold, Brower Brower (1987)
Acute coronary thrombolysis with rt‐PA: Initial patency and influence of maintained infusion on reocclusion rateAm J Cardiol, 60
(1971)
Streptokinase in Recent Myocardial Infarction: A Controlled Multicentre TrialBritish Medical Journal, 3
Schmutzler Schmutzler, Heckner Heckner, Körtge Körtge (1966)
Zur thrombolytischen therapie des frischen herzinfarktes. 1. Einführung, be‐handlungspläne, klinische ergebnisseDtsch Med Wschr, 91
Kari Pietilä, A. Harmoinen, W. Hermens, M. Simoons, F. Werf, M. Verstraete (1993)
Serum C-reactive protein and infarct size in myocardial infarct patients with a closed versus an open infarct-related coronary artery after thrombolytic therapy.European heart journal, 14 7
A. Arnold, M. Simoons, J. Detry, R. Essen, F. Werf, Jaap Deckers, J. Lubsen, M. Verstraete (1993)
Prediction of mortality following hospital discharge after thrombolysis for acute myocardial infarction: is there a need for coronary angiography? European Cooperative Study Group.European heart journal, 14 3
Werf Werf, Arnold Arnold (1988)
Effect of intravenous tissue‐type plasminogen activator on infarct size, left ventricular function and survival in patients with acute myocardial infarctionBr Med J, 297
Willems Willems, Willems Willems, Willems Willems (1990)
for the European Cooperative Study Group for rt‐PA. The significance of initial ST‐segment elevation and depression for the management of thrombolytic therapy in acute myocardial infarctionCirculation, 82
W. Schmidt, Rainer Uebis, R. Essen, S. Effert, R. Erbel, Jürgen Meyer, W. Rursch, M. Schartl, H. Schmutzler (1987)
Residual coronary stenosis after thrombolysis with rt-PA or streptokinase: acute results and 3 weeks follow-up.European heart journal, 8 11
N. Kochenour, Pantaleo Greco, E. Letsky, R. Johnson, M. Contreras, C. Rodeck (1988)
Intravenous tissue plasminogen activator and size of infarct, left ventricular function, and survival in acute myocardial infarction.British Medical Journal, 297
M. Verstraete, J. Loo, H. Jesdinsky (1981)
Streptokinase in acute myocardial infarctionActa Medica Scandinavica, 648
R. Schmutzler, F. Heckner, P. Körtge, J. Loo, F. Pezold, H. Poliwoda, F. Praetorius, D. Zekorn (1966)
Zur thrombolytischen Therapie des frischen Herzinfarktes. I. Einführung, Behandlungspläne, allgemeine klinische ErgebnisseDeutsche Medizinische Wochenschrift, 91
Arnold Arnold, Simoons Simoons, Detry Detry (1993)
for the European Cooperative Study Group. Prediction of mortality after hospital discharge in patients treated with and without recombinant tissue plasminogen activator for myocardial infarction: Is there a need for coronary angiographyEur Heart J, 14
Arnold Arnold, Simoons Simoons, Werf Werf (1992)
for the European Cooperative Study Group. Recombinant tissue‐type plasminogen activator and immediate angioplasty in acute myocardial infarction: One year follow upCirculation, 86
J. Arnout, Maarten Simoons, D. Bono, H. Rapold, D. Collen, M. Verstraete (1992)
Correlation between level of heparinization and patency of the infarct-related coronary artery after treatment of acute myocardial infarction with alteplase (rt-PA).Journal of the American College of Cardiology, 20 3
J. vandeLoo (1963)
[POSSIBILITIES AND LIMITATIONS OF COMBINED FIBRINOLYTIC-ANTICOAGULANT THERAPY OF MYOCARDIAL INFARCT].Medizinische Klinik, 58
M. Simoons, A. Betriu, J. Col, R. Essen, J. Lubsen, P. Michel, W. Rutsch, W. Schmidt, C. Théry, A. Vahanian, G. Willems, A. Arnold, D. Bono, F. Dougherty, H. Lambertz, B. Meier, P. Raynaud, G. Sanz, P. Serruys, R. Uebis, F. Werf, D. Wood, M. Verstraete, European Activator (1988)
THROMBOLYSIS WITH TISSUE PLASMINOGEN ACTIVATOR IN ACUTE MYOCARDIAL INFARCTION: NO ADDITIONAL BENEFIT FROM IMMEDIATE PERCUTANEOUS CORONARY ANGIOPLASTYThe Lancet, 331
Trials of the European Working Party on Streptokinase and of the European Cooperative Working Group on tPA in Patients with Acute Myocardial Infarction The first trial of the European Working Party was commenced in 1962 at a time when no controlled, strictly randomized, large scale trials on the clinical use of thrombolytic drugs in patients with recent myocardial infarction (MI) were available. At that time, the frequency with which a fresh thrombw complicates the coronary atheromatous lesion in acute M1 was derived from autopsy studies and reported to vary from 13%-74%.' This disparity was doubtless due in part to the selection of the patient samples (sudden, early, late deaths), to types of infarctions (transmural, subendocardial), and to the methods of postmortem study (dissection or angiography). The prevailing hypothesis that a coronary thrombus was often seconduary to a MI was based, among other things, on the fact that at autopsy a thrombus was found more frequently in the older infarcts, after cardiac shock, or after severe heart failure.* The finding that radioactive fibrinogen, given in the acute phase of MI, has been recovered in the coronary thrombus at autopsy was wrongly conqidered as an argument in EWP stccring committee:
Journal of Interventional Cardiology – Wiley
Published: Dec 1, 1995
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