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The widely occurring tetranortriterpene natural product gedunin has a well‐established range of important biological properties. Although this molecule has received substantial semi‐synthetic attention from medicinal chemists, it has not received devoted de novo synthetic attention since it was first isolated in 1960. A key feature of the approach presented herein was the decision to utilize a Robinson annulation reaction, which facilitated the installation of the challenging 7‐acetoxy functional group and the completion of the fully functionalized ABC ring system.
Asian Journal of Organic Chemistry – Wiley
Published: May 1, 2017
Keywords: ; ; ; ;
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